ID C4JZS1_UNCRE Unreviewed; 611 AA.
AC C4JZS1;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 67.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN ORFNames=UREG_07672 {ECO:0000313|EMBL:EEP82807.1};
OS Uncinocarpus reesii (strain UAMH 1704).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus.
OX NCBI_TaxID=336963 {ECO:0000313|EMBL:EEP82807.1, ECO:0000313|Proteomes:UP000002058};
RN [1] {ECO:0000313|Proteomes:UP000002058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 1704 {ECO:0000313|Proteomes:UP000002058};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; CH476619; EEP82807.1; -; Genomic_DNA.
DR RefSeq; XP_002582899.1; XM_002582853.1.
DR AlphaFoldDB; C4JZS1; -.
DR STRING; 336963.C4JZS1; -.
DR GeneID; 8439688; -.
DR KEGG; ure:UREG_07672; -.
DR VEuPathDB; FungiDB:UREG_07672; -.
DR eggNOG; KOG0305; Eukaryota.
DR HOGENOM; CLU_014831_4_0_1; -.
DR InParanoid; C4JZS1; -.
DR OMA; WSKNTDE; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000002058; Unassembled WGS sequence.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF1; FIZZY-RELATED PROTEIN HOMOLOG; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002058};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 346..399
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 426..458
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 468..512
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 556..597
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..63
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 611 AA; 68102 MW; C3E95E177B881EF9 CRC64;
MAERRSDGNR VKPSHARAKS DRATMPGNLV SPPSSNTPPT VRTKSHSLHT GPEPAKFRSR
LGSEPINAGA LAKALKDFED VGRQRERTPG TSPCRKRQRV YGDRFIPNRE GQDLQASYSL
LHEDGCPSTP SKTKRRPPHG EIHFQRSKGS IRILANYLSD EFDVAEEANR TYSRILRNEF
FGDSIPQSDL NTLSPEATTT YTTSHDPTRS HTPPSYKAAS SLPPASITPS TPSKNLFSYS
SPRKASENPT PSRTPHSGSN FNARSDIYSL SPIRFDSQRM LQGLRKQPRY INKVPFKVLD
APELADDFYL NLVDWGSTNI LGVGLGAAVY MWDSVNGNVT KLCELKDDTV TSVSWIQRGT
HLAIGTGRGF VQIWDAENCR RLRTMTGHTL RVGALAWNDH ILTSGSRDRI IYHRDVRSPD
QYLRRLTGHK QEICGLKWNT EDGQLASGGN DNKLLVWDKL SETPLYRFSD HNAAVKAIAW
SPHQHSLLAS GGGTADRTIK FWNTATGSLI KEVDTGSQVC NLAWSKNSDE IVSTHGYSQN
QIVVWKYPRM EQIASLTGHT FRVLYLAMSP DGQTVVTGAG DETLRFWKIF NKKGLKDQNR
ESKLSGLTTI R
//
