ID C4KJ58_SULIK Unreviewed; 457 AA.
AC C4KJ58;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=cellulose synthase (UDP-forming) {ECO:0000256|ARBA:ARBA00012539};
DE EC=2.4.1.12 {ECO:0000256|ARBA:ARBA00012539};
GN OrderedLocusNames=M164_2019 {ECO:0000313|EMBL:ACR42622.1};
OS Sulfolobus islandicus (strain M.16.4 / Kamchatka #3).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=426118 {ECO:0000313|EMBL:ACR42622.1, ECO:0000313|Proteomes:UP000001479};
RN [1] {ECO:0000313|EMBL:ACR42622.1, ECO:0000313|Proteomes:UP000001479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M.16.4 / Kamchatka #3 {ECO:0000313|Proteomes:UP000001479};
RX PubMed=19435847; DOI=10.1073/pnas.0808945106;
RA Reno M.L., Held N.L., Fields C.J., Burke P.V., Whitaker R.J.;
RT "Biogeography of the Sulfolobus islandicus pan-genome.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:8605-8610(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001402; ACR42622.1; -; Genomic_DNA.
DR RefSeq; WP_012736085.1; NC_012726.1.
DR AlphaFoldDB; C4KJ58; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR GeneID; 84062324; -.
DR KEGG; sid:M164_2019; -.
DR HOGENOM; CLU_041759_1_0_2; -.
DR Proteomes; UP000001479; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IEA:UniProtKB-KW.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43867; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR PANTHER; PTHR43867:SF2; CELLULOSE SYNTHASE CATALYTIC SUBUNIT A [UDP-FORMING]; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 4: Predicted;
KW Cellulose biosynthesis {ECO:0000256|ARBA:ARBA00022916};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACR42622.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 5..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 333..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 49..219
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
SQ SEQUENCE 457 AA; 51530 MW; 95B294AAB2EFEA41 CRC64;
MLNLLLNLAI FIVPSLVVWN QIIFYIYGKN YNAVNLILHD NGINLPKLSI IVPTKGERID
VIQGLINNIY EARWDKNKLE IIIVSDDDQA YFDKLLSTLI IPPGLDVKIF RREKRLGYKS
GALAFGLQKS TGDLILTLDV DARIEKDSLI RAYNHMVNLG CDAVTMEWHG YSNISTSLAR
ALMVSTVLTS RSILRGRDKL GLKVLPIGCG TIFKRNALEA VNGWDYTMVQ DDYELGTRLI
NRGFRICASS SPVYVEVPDN LIAFYVQQTR WAMGTMEVLS RRFKYIVSSN IKIWQKIEII
AYLSQYIPII LTFISATVFG IAGFLGIRLS MSLPMFVIWA ITLSVYAIIF VNSSKRSGLD
TITAINALGR LSAYTVGISP FLLVGTLNAF KKTRTYIVTP KGKKAKSNIG YPILAFGIFF
LLSAFLYMFR GDFLTFIWLA YYSIAFLYTF IAYIKGL
//
