ID C4LC24_TOLAT Unreviewed; 299 AA.
AC C4LC24;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=NAD-dependent epimerase/dehydratase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=Tola_0875 {ECO:0000313|EMBL:ACQ92503.1};
OS Tolumonas auensis (strain DSM 9187 / TA4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Aeromonadaceae; Tolumonas.
OX NCBI_TaxID=595494 {ECO:0000313|EMBL:ACQ92503.1, ECO:0000313|Proteomes:UP000009073};
RN [1] {ECO:0000313|Proteomes:UP000009073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4 {ECO:0000313|Proteomes:UP000009073};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S.,
RA Beller H.;
RT "Complete sequence of Tolumonas auensis DSM 9187.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ACQ92503.1, ECO:0000313|Proteomes:UP000009073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 9187 / TA4 {ECO:0000313|Proteomes:UP000009073};
RX PubMed=22180815; DOI=10.4056/sigs.2184986;
RA Chertkov O., Copeland A., Lucas S., Lapidus A., Berry K.W., Detter J.C.,
RA Del Rio T.G., Hammon N., Dalin E., Tice H., Pitluck S., Richardson P.,
RA Bruce D., Goodwin L., Han C., Tapia R., Saunders E., Schmutz J.,
RA Brettin T., Larimer F., Land M., Hauser L., Spring S., Rohde M.,
RA Kyrpides N.C., Ivanova N., Goker M., Beller H.R., Klenk H.P., Woyke T.;
RT "Complete genome sequence of Tolumonas auensis type strain (TA 4).";
RL Stand. Genomic Sci. 5:112-120(2011).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. SDR39U1 subfamily. {ECO:0000256|ARBA:ARBA00009353}.
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DR EMBL; CP001616; ACQ92503.1; -; Genomic_DNA.
DR RefSeq; WP_012729102.1; NC_012691.1.
DR AlphaFoldDB; C4LC24; -.
DR STRING; 595494.Tola_0875; -.
DR KEGG; tau:Tola_0875; -.
DR eggNOG; COG1090; Bacteria.
DR HOGENOM; CLU_047373_0_3_6; -.
DR OrthoDB; 9801773at2; -.
DR Proteomes; UP000009073; Chromosome.
DR CDD; cd05242; SDR_a8; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013549; DUF1731.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR010099; SDR39U1.
DR NCBIfam; TIGR01777; yfcH; 1.
DR PANTHER; PTHR11092:SF0; EPIMERASE FAMILY PROTEIN SDR39U1; 1.
DR PANTHER; PTHR11092; SUGAR NUCLEOTIDE EPIMERASE RELATED; 1.
DR Pfam; PF08338; DUF1731; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000009073}.
FT DOMAIN 3..222
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 250..296
FT /note="DUF1731"
FT /evidence="ECO:0000259|Pfam:PF08338"
SQ SEQUENCE 299 AA; 33227 MW; 2E92BCB2EBD3DA0F CRC64;
MKILITGATG FIGQYLVSLL RAEHELLLVS RQPELAAKQL AVDNSKVIQL KQLNSLDGVD
AIINLAGESL AAKRWSVEQK RRISESRWLM TETLLEKLKN STPAPRVWIN ASAIGFYGAQ
GAEPLDESFT PSQTNFPNRV CAHWEELAQQ ASAFNCRVCI MRIGLVLGTQ GGALARMLPA
YWCGLGGPLG SGKQMVSWIT RTDLVYIIRF LLEHSQCSGI YNATSPQAVS NAQFSAALAT
ALHRPHFLRT PAWMLRLLLG EMADLLLTGQ NVQPRRLLEA GFRFRYPELP EALRHIFED
//
