ID C4LGK9_CORK4 Unreviewed; 468 AA.
AC C4LGK9;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 67.
DE SubName: Full=Cyclopropane-fatty-acyl-phospholipid synthase {ECO:0000313|EMBL:ACR16964.1};
DE EC=2.1.1.79 {ECO:0000313|EMBL:ACR16964.1};
GN Name=cfa1 {ECO:0000313|EMBL:ACR16964.1};
GN OrderedLocusNames=ckrop_0172 {ECO:0000313|EMBL:ACR16964.1};
OS Corynebacterium kroppenstedtii (strain DSM 44385 / JCM 11950 / CIP 105744 /
OS CCUG 35717).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=645127 {ECO:0000313|EMBL:ACR16964.1, ECO:0000313|Proteomes:UP000001473};
RN [1] {ECO:0000313|EMBL:ACR16964.1, ECO:0000313|Proteomes:UP000001473}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44385 / JCM 11950 / CIP 105744 / CCUG 35717
RC {ECO:0000313|Proteomes:UP000001473};
RX PubMed=18430482; DOI=10.1016/j.jbiotec.2008.03.004;
RA Tauch A., Schneider J., Szczepanowski R., Tilker A., Viehoever P.,
RA Gartemann K.-H., Arnold W., Blom J., Brinkrolf K., Brune I., Goetker S.,
RA Weisshaar B., Goesmann A., Droege M., Puehler A.;
RT "Ultrafast pyrosequencing of Corynebacterium kroppenstedtii DSM44385
RT revealed insights into the physiology of a lipophilic corynebacterium that
RT lacks mycolic acids.";
RL J. Biotechnol. 136:22-30(2008).
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
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DR EMBL; CP001620; ACR16964.1; -; Genomic_DNA.
DR AlphaFoldDB; C4LGK9; -.
DR STRING; 645127.ckrop_0172; -.
DR KEGG; ckp:ckrop_0172; -.
DR eggNOG; COG2230; Bacteria.
DR HOGENOM; CLU_026434_6_2_11; -.
DR Proteomes; UP000001473; Chromosome.
DR GO; GO:0008825; F:cyclopropane-fatty-acyl-phospholipid synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003333; CMAS.
DR InterPro; IPR020803; PKS_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43667; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR PANTHER; PTHR43667:SF1; CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE; 1.
DR Pfam; PF02353; CMAS; 1.
DR PIRSF; PIRSF003085; CMAS; 1.
DR SMART; SM00828; PKS_MT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Methyltransferase {ECO:0000313|EMBL:ACR16964.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001473};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ACR16964.1}.
FT DOMAIN 197..431
FT /note="Polyketide synthase methyltransferase"
FT /evidence="ECO:0000259|SMART:SM00828"
SQ SEQUENCE 468 AA; 51591 MW; 8F177CD1FD31C892 CRC64;
MVKIPGLARH ATSMVGADPT IMSALISTPL TKLIRPASHP MTVGEIIDAI ADFPIRVTAF
DGSSAGGTNG AATSADASGD MGIHITKDGL AYIATAPGEL GLARAYLTDN LRVSGTHPAN
PYDLFGVLRT VRLKKLSPST VRRIIGSLAA MDAFRNLPQP PQEMVPFWQR AIDGLSRHSQ
QRDAESISHH YDVSNRFYEL FLGPSMTYTC AYYPDPSATL EEAQENKYRL IFDKLRLQPG
DTLLDVGCGW GGMVRYAARH GVKAIGATLS REQAEWANEE IARQGLSDRA EVRFQDYRDI
PETDFDAISA IGILEHIGTA NYHDFFSFLF NKLRPGGLIL NHCITRPINE AKTNAGPFLD
RYIFPDGELH CSGNIIANMQ GAGFEVMHEE NLRPHYARTL KAWCNNLEEN WDAACEEVSE
ATAKLYGVYM AGSAWGFDHN IVQLHQALGV KPLQDGTMAV PEHQWWES
//
