ID   C4QW27_KOMPG            Unreviewed;      1250 AA.
AC   C4QW27;
DT   07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   07-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CAY67450.1};
GN   OrderedLocusNames=PAS_chr1-1_0090 {ECO:0000313|EMBL:CAY67450.1};
OS   Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Phaffomycetaceae; Komagataella.
OX   NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY67450.1, ECO:0000313|Proteomes:UP000000314};
RN   [1] {ECO:0000313|EMBL:CAY67450.1, ECO:0000313|Proteomes:UP000000314}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX   PubMed=19465926; DOI=10.1038/nbt.1544;
RA   De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA   Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT   "Genome sequence of the recombinant protein production host Pichia
RT   pastoris.";
RL   Nat. Biotechnol. 27:561-566(2009).
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DR   EMBL; FN392319; CAY67450.1; -; Genomic_DNA.
DR   RefSeq; XP_002489731.1; XM_002489686.1.
DR   AlphaFoldDB; C4QW27; -.
DR   SMR; C4QW27; -.
DR   STRING; 644223.C4QW27; -.
DR   EnsemblFungi; CAY67450; CAY67450; PAS_chr1-1_0090.
DR   GeneID; 8197216; -.
DR   KEGG; ppa:PAS_chr1-1_0090; -.
DR   eggNOG; ENOG502QQWJ; Eukaryota.
DR   HOGENOM; CLU_003023_1_0_1; -.
DR   InParanoid; C4QW27; -.
DR   OMA; VLKSPKW; -.
DR   OrthoDB; 1984726at2759; -.
DR   Proteomes; UP000000314; Chromosome 1.
DR   CDD; cd04043; C2_Munc13_fungal; 1.
DR   Gene3D; 1.10.357.50; -; 1.
DR   Gene3D; 1.20.58.1100; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR014770; Munc13_1.
DR   InterPro; IPR014772; Munc13_dom-2.
DR   PANTHER; PTHR47263; ADENYLATE CYCLASE ACTIVATION PROTEIN GIT1; 1.
DR   PANTHER; PTHR47263:SF1; C2 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_7G02350); 1.
DR   Pfam; PF00168; C2; 1.
DR   SMART; SM00239; C2; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
DR   PROSITE; PS51258; MHD1; 1.
DR   PROSITE; PS51259; MHD2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT   DOMAIN          578..700
FT                   /note="MHD1"
FT                   /evidence="ECO:0000259|PROSITE:PS51258"
FT   DOMAIN          786..912
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   DOMAIN          992..1130
FT                   /note="MHD2"
FT                   /evidence="ECO:0000259|PROSITE:PS51259"
SQ   SEQUENCE   1250 AA;  142798 MW;  8FB879B077E0B4D1 CRC64;
     MYNRYSPFTH LSQMSVDISS LSISGTGFDE IAMDQYHQIL KVAIASYRVE PRFRKRVLPR
     HVSNDENSDS HFKKPKVIKV SSRTISDLRK YLNPLKKGKP VKLISTSLST QVFNALLTYL
     TKLDKSKQLE TIEKPENFLR QFMLIATREL KTLKGQMFMD SLDTQTTIFL SIMQEVVKND
     KEGDSIMKKL QEARFTLSSS SNNVNDFEYI MPSFKLSEMS LAQHVGAIFQ IDDKELQNDI
     LSLKNNITPD KIIHDQKTYL VNCLKQQHLV YQKRDFLDSS SFTNWLKVES LNTENYISQI
     DSKPVNLCEP SAFFNLVPRS SALYYQTLLE KCMRYDSRMN ASSNTPLLST SSRELIEECV
     KIWRIDAFTA MIYFFKTSCS TVLSTSDGSI NSDLFFLVLN LMKKYLTDLK LSIDKSTWPS
     KTRLEWIDCL EICYLKTMKG IQTCISQVLT SKPPFSQYLN VLAEIEQDSL FRNIVAKHVP
     DKLEKQLIHK LNDTILLRYK DLLTEIPTDN TIDLIHIADL SRKIVEDTKM LQKRYKHPLL
     GKIPIAPTYA KRIITDFAVD AKYMLKSIKQ NSADISFADA LDIYKTLSEI RDIFTQVTDT
     PFKFDLEKGF YKYLKNWAIN ASEQIVAVTN TAVAQDDLGC ASPENDILYS TSVKDIFMMI
     NQNVSFLKDL NWKNEYHLAK VSTLLFQYIS MALITYCDKM YDTIVADLDE EDQKNVATTL
     PGETNSYDSL LSGTSAWIAD MKAAVTRSQK LTPPEPYAFK NRTCVALNNI VQCLQNLDEL
     EDILDPEYVS NVMNRENPSI FKEYTNHFFT IKVVQAEGIK SPVGKDAPDA NVWLSNNNTK
     KVFARTRTIP SSDRPEWDEE FEVVLFPGAS VSILATLWDK SFKRFSSDAV IGRTLFHLSP
     KEFNNNGIPR DLILNLDTEG TLVLQVSLES EREDALFCMG KTRRSLIHAR DRVIKLMVGK
     FSPFIQFAFS RDVLKNACGS NGLLLISEEQ RIDVILPLFD YLNSNLDILA RILPESLLQK
     VILQMWNVVL ASAEHLILPL LSTVKMAKNS NKLWSNINFN SGMNIAGFGR PLTPLEVKTV
     FEWLHVLCYE QFYNEGEGAS LEKLQNYQYK LLLKVSEHYE KPVGEILSKV RECEPMTIEH
     IRERNYFYIT VDSKEKKLTR AATIARQKTI GAQGSKKQMH KAAEDVKIAQ ETDSNANAAA
     FEDMLLRILL TKGEMGFVAE RLEQREKFTQ SVSAESFARA AAAGAFNGIR
//