ID C4QWB7_KOMPG Unreviewed; 247 AA.
AC C4QWB7;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Dihydrodipicolinate synthase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=PAS_chr1-1_0175 {ECO:0000313|EMBL:CAY67540.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY67540.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY67540.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|ARBA:ARBA00007592}.
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DR EMBL; FN392319; CAY67540.1; -; Genomic_DNA.
DR RefSeq; XP_002489821.1; XM_002489776.1.
DR AlphaFoldDB; C4QWB7; -.
DR SMR; C4QWB7; -.
DR STRING; 644223.C4QWB7; -.
DR EnsemblFungi; CAY67540; CAY67540; PAS_chr1-1_0175.
DR GeneID; 8196679; -.
DR KEGG; ppa:PAS_chr1-1_0175; -.
DR HOGENOM; CLU_049343_1_0_1; -.
DR InParanoid; C4QWB7; -.
DR OMA; MVGNVYP; -.
DR OrthoDB; 2047899at2759; -.
DR Proteomes; UP000000314; Chromosome 1.
DR GO; GO:0016829; F:lyase activity; IEA:InterPro.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR InterPro; IPR020625; Schiff_base-form_aldolases_AS.
DR PANTHER; PTHR12128:SF72; 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS00666; DHDPS_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Schiff base {ECO:0000256|ARBA:ARBA00023270}.
SQ SEQUENCE 247 AA; 27891 MW; 788FDB0D6802DADF CRC64;
MNSVKEDFHI AVPTAFHADE SLNIEETLKH IDHSLDQEAR FAPDLEILVG VSGIRQKEVL
RLAERVERSN AIKAVLLGYP PYLVPSQAEA VCYTEKVLEK LSKPVILYNN PLRTGFDLAV
ESILHLFDNH QIIGIKEAGD PEKIQAVQKR LDRTVYYYAG GEQDLEKKIS LGFNRLSSIA
GNVWPQEISN WFFNLLEGKN DDTDKISLLL ENLYNDSFLV QLKKLIIATS DVQMGNCRAP
LGNLEKE
//
