ID C4QXX3_KOMPG Unreviewed; 674 AA.
AC C4QXX3;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Protein required for maturation of the 25S and 5.8S ribosomal RNAs {ECO:0000313|EMBL:CAY68096.1};
GN OrderedLocusNames=PAS_chr1-4_0263 {ECO:0000313|EMBL:CAY68096.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY68096.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY68096.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
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DR EMBL; FN392319; CAY68096.1; -; Genomic_DNA.
DR RefSeq; XP_002490377.1; XM_002490332.1.
DR AlphaFoldDB; C4QXX3; -.
DR SMR; C4QXX3; -.
DR STRING; 644223.C4QXX3; -.
DR EnsemblFungi; CAY68096; CAY68096; PAS_chr1-4_0263.
DR GeneID; 8196935; -.
DR KEGG; ppa:PAS_chr1-4_0263; -.
DR eggNOG; KOG0035; Eukaryota.
DR HOGENOM; CLU_434105_0_0_1; -.
DR InParanoid; C4QXX3; -.
DR OrthoDB; 2872403at2759; -.
DR Proteomes; UP000000314; Chromosome 1.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR044801; Filamin.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR PANTHER; PTHR38537:SF17; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 2.
DR SMART; SM00033; CH; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 8..115
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 129..233
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 537..572
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 674 AA; 78292 MW; 02314878DBA3803B CRC64;
MAKTDWVETQ TRTFTNWINS KLRSIDEAPI KDIRKDFSDG LKLLKLLYAL SEDTSLQPVH
SRPFLSVQKM ENVAVSLEFM KFNGLQLHNI GSDDIVEGNL KLLLGLIWTI ISHYTIVKHS
SDSKDRGFGD KRSFLLAWVQ SVTSKYNVHV SNFSTSWNDG KALSALYAAH CSGKFQFSNQ
DWSDRKLVIT TVLTLAEHEL CIPKLIQPQD LLQVEPDEKS VMLYIVEWYM RFAHTSESSL
GSISRSASAN FSIDEPNTPD TEYTIDEQLH ITKFVKVTES LKRLQGAFDT RAEALVERIK
LWIRHFETLY LKYDEYEKLD EIDTQSIDKL VDILVKERSN LLDFSSSEKL PMLQERVELR
TLLSKIKIKT SRYAFAPYNP DITLHDIDNL WTSLLQIEST FSTITDDLTR NAQATVYSRF
FSKVNEFQQH VFTQNKKLFE VLSMDSLEYQ VEELKKLSEQ IKKFDSLFLE LSLLFEKLEK
YHTAHLLTNM EYDECKLQFN ELENWLTNIF KLQIIDRLKF IEEEYACSTD SYDIPDWQLN
NCKQLFQECD IGAKGYLNKS EFTTCMERVF NDDNKLPVSE IHEIFESDIN QNNNTLRGLK
LEAFLSTVGS LLENETIELD KELSSSLQKY FKTLNENAQG YDKVQQIVTE LTNAPLSQFV
VDLERLSIDS RNEQ
//
