ID C4R2X7_KOMPG Unreviewed; 203 AA.
AC C4R2X7;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 76.
DE SubName: Full=GTPase of the Ras superfamily required to recruit Arl1p to the Golgi {ECO:0000313|EMBL:CAY69851.1};
GN OrderedLocusNames=PAS_chr2-2_0078 {ECO:0000313|EMBL:CAY69851.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY69851.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY69851.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000256|ARBA:ARBA00004555}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Arf family.
CC {ECO:0000256|ARBA:ARBA00010290}.
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DR EMBL; FN392320; CAY69851.1; -; Genomic_DNA.
DR RefSeq; XP_002492131.1; XM_002492086.1.
DR AlphaFoldDB; C4R2X7; -.
DR SMR; C4R2X7; -.
DR STRING; 644223.C4R2X7; -.
DR EnsemblFungi; CAY69851; CAY69851; PAS_chr2-2_0078.
DR GeneID; 8199182; -.
DR KEGG; ppa:PAS_chr2-2_0078; -.
DR eggNOG; KOG0076; Eukaryota.
DR HOGENOM; CLU_040729_7_2_1; -.
DR InParanoid; C4R2X7; -.
DR OMA; HGFYKYM; -.
DR OrthoDB; 5349301at2759; -.
DR Proteomes; UP000000314; Chromosome 2.
DR GO; GO:0005794; C:Golgi apparatus; IEA:EnsemblFungi.
DR GO; GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IEA:EnsemblFungi.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:EnsemblFungi.
DR GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:EnsemblFungi.
DR GO; GO:0006886; P:intracellular protein transport; IEA:EnsemblFungi.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IEA:EnsemblFungi.
DR GO; GO:0034976; P:response to endoplasmic reticulum stress; IEA:EnsemblFungi.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR006689; Small_GTPase_ARF/SAR.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR45909; ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1; 1.
DR PANTHER; PTHR45909:SF1; ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1; 1.
DR Pfam; PF00025; Arf; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00178; SAR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51419; RAB; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
SQ SEQUENCE 203 AA; 23060 MW; 088FCA4EB16BC8F5 CRC64;
MFHLAKGLYQ NWNRKEQYSV LILGLDNAGK TTFLERVKSI YMPNAKITPP ERILPTVGQN
VGIINFSSKV NLKFWDVGGQ ESLREMWSEY YTNSHAIIFV IDSTDKDRLL DCQKALSSIV
TDDLIEGIPI LMLANKQDVE GAPGKLEVED IKEIFNVIAE HLDARDSRVL PISAKTGDGV
QQSIEWLTLR LERNKSNKPP IYR
//
