ID C4R423_KOMPG Unreviewed; 187 AA.
AC C4R423;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 64.
DE SubName: Full=Coenzyme Q (Ubiquinone) binding protein {ECO:0000313|EMBL:CAY70309.1};
GN OrderedLocusNames=PAS_chr3_0270 {ECO:0000313|EMBL:CAY70309.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY70309.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY70309.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC chain. May serve as a chaperone or may be involved in the transport of
CC Q6 from its site of synthesis to the catalytic sites of the respiratory
CC complexes. {ECO:0000256|ARBA:ARBA00024947}.
CC -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000256|ARBA:ARBA00011814}.
CC -!- SIMILARITY: Belongs to the COQ10 family.
CC {ECO:0000256|ARBA:ARBA00006885}.
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DR EMBL; FN392321; CAY70309.1; -; Genomic_DNA.
DR RefSeq; XP_002492488.1; XM_002492443.1.
DR AlphaFoldDB; C4R423; -.
DR STRING; 644223.C4R423; -.
DR EnsemblFungi; CAY70309; CAY70309; PAS_chr3_0270.
DR GeneID; 8200098; -.
DR KEGG; ppa:PAS_chr3_0270; -.
DR eggNOG; KOG3177; Eukaryota.
DR HOGENOM; CLU_079653_1_2_1; -.
DR InParanoid; C4R423; -.
DR OMA; IDGPFKY; -.
DR OrthoDB; 2722348at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0048039; F:ubiquinone binding; IEA:InterPro.
DR GO; GO:0045333; P:cellular respiration; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07813; COQ10p_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR044996; COQ10-like.
DR InterPro; IPR005031; COQ10_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR12901:SF10; COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12901; SPERM PROTEIN HOMOLOG; 1.
DR Pfam; PF03364; Polyketide_cyc; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT DOMAIN 50..175
FT /note="Coenzyme Q-binding protein COQ10 START"
FT /evidence="ECO:0000259|Pfam:PF03364"
SQ SEQUENCE 187 AA; 21488 MW; 87A2784AD7BAF81F CRC64;
MMAKRSRIQH FKSISWVSSR TFLNLGRLAQ NSELKGNGQQ YVVKKTFHQP KSVVYNVISN
VDKYHEFIPY CEASFINSRD TKGEPTEAGL TVGFKSFDET FLCTLECQKD KQVIAKSITH
SLFHNLLTEW NVTEASSSKT NVELILSYEF KSDLYNQVSA LFASKVTSIM IKAFEKRAYT
EHKQFCK
//
