ID C4R566_KOMPG Unreviewed; 337 AA.
AC C4R566;
DT 07-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 07-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 75.
DE SubName: Full=Phosphatidylinositol/phosphatidylcholine transfer protein {ECO:0000313|EMBL:CAY70702.1};
GN OrderedLocusNames=PAS_chr3_0655 {ECO:0000313|EMBL:CAY70702.1};
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223 {ECO:0000313|EMBL:CAY70702.1, ECO:0000313|Proteomes:UP000000314};
RN [1] {ECO:0000313|EMBL:CAY70702.1, ECO:0000313|Proteomes:UP000000314}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864 {ECO:0000313|Proteomes:UP000000314};
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
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DR EMBL; FN392321; CAY70702.1; -; Genomic_DNA.
DR RefSeq; XP_002492881.1; XM_002492836.1.
DR AlphaFoldDB; C4R566; -.
DR SMR; C4R566; -.
DR STRING; 644223.C4R566; -.
DR EnsemblFungi; CAY70702; CAY70702; PAS_chr3_0655.
DR GeneID; 8199853; -.
DR KEGG; ppa:PAS_chr3_0655; -.
DR eggNOG; KOG1471; Eukaryota.
DR HOGENOM; CLU_014001_0_1_1; -.
DR InParanoid; C4R566; -.
DR OMA; WAFSTVW; -.
DR OrthoDB; 6048at2759; -.
DR Proteomes; UP000000314; Chromosome 3.
DR GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR GO; GO:0000139; C:Golgi membrane; IEA:EnsemblFungi.
DR GO; GO:0008525; F:phosphatidylcholine transporter activity; IEA:EnsemblFungi.
DR GO; GO:0008526; F:phosphatidylinositol transfer activity; IEA:EnsemblFungi.
DR GO; GO:0030437; P:ascospore formation; IEA:EnsemblFungi.
DR GO; GO:0043001; P:Golgi to plasma membrane protein transport; IEA:EnsemblFungi.
DR GO; GO:0006896; P:Golgi to vacuole transport; IEA:EnsemblFungi.
DR GO; GO:0048194; P:Golgi vesicle budding; IEA:EnsemblFungi.
DR GO; GO:2001246; P:negative regulation of phosphatidylcholine biosynthetic process; IEA:EnsemblFungi.
DR GO; GO:1901352; P:negative regulation of phosphatidylglycerol biosynthetic process; IEA:EnsemblFungi.
DR GO; GO:0046488; P:phosphatidylinositol metabolic process; IEA:EnsemblFungi.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 1.10.8.20; N-terminal domain of phosphatidylinositol transfer protein sec14p; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011074; CRAL/TRIO_N_dom.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR PANTHER; PTHR45657; CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED; 1.
DR PANTHER; PTHR45657:SF1; CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF03765; CRAL_TRIO_N; 1.
DR PRINTS; PR00180; CRETINALDHBP.
DR SMART; SM01100; CRAL_TRIO_N; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000314}.
FT DOMAIN 132..305
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
SQ SEQUENCE 337 AA; 38484 MW; 2C3F2FAA40236F5A CRC64;
MDIIAHQIPR SPGISTLEIT KIISSQQLRT MSEVTRTNNN SASYPSETAP SEMGLTGYPG
HLTDEEKKTL ETFREGLKAA GYTQRLDDST LLRFLRARKF DVAKATEMFV NCEKWRKKEN
VDHILEEFHY EEKPLVAQMY PTYYHKTDKD GRPVYYEELG RVNINEMLKI TTQERMVKNL
VWEYESFVKF RLPACSRKSG VLIETSCTIL DLKGITISSA YSVMGYVKEV SYIGQNYYPE
RMGKFYLINA PFGFSTAFKI FKPFLDPVSV SKIFILGSSY KSELLRQIPK ENLPVKFGGE
SEVPDSEGGL LLSDIGPWRE PEFIGPEGEA PHVFSLK
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