ID C4XFX9_MYCFP Unreviewed; 553 AA.
AC C4XFX9;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=arginine--tRNA ligase {ECO:0000256|ARBA:ARBA00012837};
DE EC=6.1.1.19 {ECO:0000256|ARBA:ARBA00012837};
GN OrderedLocusNames=MBIO_0786 {ECO:0000313|EMBL:BAH70051.1};
OS Mycoplasmopsis fermentans (strain ATCC 19989 / NBRC 14854 / NCTC 10117 /
OS PG18) (Mycoplasma fermentans).
OC Bacteria; Mycoplasmatota; Mycoplasmoidales; Metamycoplasmataceae;
OC Mycoplasmopsis.
OX NCBI_TaxID=496833 {ECO:0000313|EMBL:BAH70051.1, ECO:0000313|Proteomes:UP000006810};
RN [1] {ECO:0000313|EMBL:BAH70051.1, ECO:0000313|Proteomes:UP000006810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19989 / NBRC 14854 / NCTC 10117 / PG18
RC {ECO:0000313|Proteomes:UP000006810};
RX PubMed=19219498; DOI=10.1007/s00284-009-9362-6;
RA Ishida N., Irikura D., Matsuda K., Sato S., Asano K.;
RT "Molecular cloning and expression of a novel cholinephosphotransferase
RT involved in glycoglycerophospholipid biosynthesis of Mycoplasma
RT fermentans.";
RL Curr. Microbiol. 58:535-540(2009).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-
CC tRNA(Arg); Xref=Rhea:RHEA:20301, Rhea:RHEA-COMP:9658, Rhea:RHEA-
CC COMP:9673, ChEBI:CHEBI:30616, ChEBI:CHEBI:32682, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:78513, ChEBI:CHEBI:456215;
CC EC=6.1.1.19; Evidence={ECO:0000256|ARBA:ARBA00001766};
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363038}.
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DR EMBL; AP009608; BAH70051.1; -; Genomic_DNA.
DR AlphaFoldDB; C4XFX9; -.
DR KEGG; mfp:MBIO_0786; -.
DR PATRIC; fig|496833.3.peg.379; -.
DR eggNOG; COG0018; Bacteria.
DR HOGENOM; CLU_501365_0_0_14; -.
DR Proteomes; UP000006810; Chromosome.
DR GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR001278; Arg-tRNA-ligase.
DR InterPro; IPR035684; ArgRS_core.
DR InterPro; IPR008909; DALR_anticod-bd.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR PANTHER; PTHR11956:SF5; ARGININE--TRNA LIGASE, CYTOPLASMIC-RELATED; 1.
DR PANTHER; PTHR11956; ARGINYL-TRNA SYNTHETASE; 1.
DR Pfam; PF05746; DALR_1; 1.
DR Pfam; PF00750; tRNA-synt_1d; 1.
DR PRINTS; PR01038; TRNASYNTHARG.
DR SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|RuleBase:RU363038};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363038};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363038};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363038};
KW Protein biosynthesis {ECO:0000256|RuleBase:RU363038};
KW Reference proteome {ECO:0000313|Proteomes:UP000006810}.
FT DOMAIN 122..409
FT /note="Arginyl-tRNA synthetase catalytic core"
FT /evidence="ECO:0000259|Pfam:PF00750"
FT DOMAIN 451..551
FT /note="DALR anticodon binding"
FT /evidence="ECO:0000259|Pfam:PF05746"
SQ SEQUENCE 553 AA; 65077 MW; F8522F5639CF0C63 CRC64;
MYLKIYSGSN MVIVHKLNKL IKNIVNELKA ENKIFSSFKF LDGEKKFSLK MARKTKGHNN
NINHIECDIV FQLKKFSFIP YIELAEEIKK RLIKDSMVKD VTIDRYGLLH IVLNEKDLVS
VVNEVIKKAY KYGQEKKNNI KVNIEYTSAS PLNSLTLMNA RNALVGETIA RILEYLGYQV
TREFLVYPGL KKMEKVSQIV HEQYVNLFEL NDNSIKVDKD ILECAKNIKA QNGDLYLDIN
DTIKRNKFDL AIVFYFLNKS KKQLKNLGVF FDIVSYFEDI LVKEKIDKVL ELLSPFIYDN
DSNLILNTNL DDSKERILVH RNGTSSYLLL DIIYHLEKLK RADWIIDILD ANHTQYSHSL
ISALKFLNAY NNNIDIAFCE NFQIKENNEV KSMTEKNQNV IFIDELVKKV NLNEIKFFFL
EKSTKHQITI EKEILNQKKI SHNFDFILNT YNKINKLLDE SKNNKCYCNK MNQNNFLSKL
ILRLDYFPYV LRKVIKTLNP FYLTKYLKEM CYLINQNLKD KLKKDYRNFY PILEAVKNVF
DNGLNLLGID FKN
//
