ID C4XWB5_CLAL4 Unreviewed; 391 AA.
AC C4XWB5;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 22-FEB-2023, entry version 55.
DE RecName: Full=Sulfite reductase [NADPH] flavoprotein alpha-component-like FAD-binding domain-containing protein {ECO:0000259|Pfam:PF00667};
GN ORFNames=CLUG_00238 {ECO:0000313|EMBL:EEQ36115.1};
OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Metschnikowiaceae; Clavispora.
OX NCBI_TaxID=306902 {ECO:0000313|EMBL:EEQ36115.1, ECO:0000313|Proteomes:UP000007703};
RN [1] {ECO:0000313|EMBL:EEQ36115.1, ECO:0000313|Proteomes:UP000007703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42720 {ECO:0000313|EMBL:EEQ36115.1,
RC ECO:0000313|Proteomes:UP000007703};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CH408076; EEQ36115.1; -; Genomic_DNA.
DR RefSeq; XP_002619079.1; XM_002619033.1.
DR AlphaFoldDB; C4XWB5; -.
DR STRING; 306902.C4XWB5; -.
DR GeneID; 8499889; -.
DR KEGG; clu:CLUG_00238; -.
DR VEuPathDB; FungiDB:CLUG_00238; -.
DR HOGENOM; CLU_705977_0_0_1; -.
DR InParanoid; C4XWB5; -.
DR OrthoDB; 5488444at2759; -.
DR Proteomes; UP000007703; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR19384:SF109; SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007703}.
FT DOMAIN 264..383
FT /note="Sulfite reductase [NADPH] flavoprotein alpha-
FT component-like FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF00667"
SQ SEQUENCE 391 AA; 43279 MW; F000A5A25161EC50 CRC64;
MLSTRSESWH SLCLWTTPRN VSIRNKFDTS VGGGIFHSQI ISSSSPDSSS AVDSADVVFV
EDASILSSFD VLATAKPGAT ILLANHKKIA TTVEQDFVEK LPVEFKRTLS KNHLQLTVVD
FSIVDELDAL SDSTKGFSAD FLAQVAFWRA AMPDLGGFVV NKLLQANGNN FELLAAVLDK
FVATVDEKQA LKSVSVPSEW AYLEDAEEEE DSLPLPYFPS ETSFFPNPRV EPASAEESAH
VGVSDLAAKL AFPEAFGVSK ELRPDLPVKN FVVKVQENKR LTPSEYSRNI FHIEFDITGT
GLTYEIGEAL GIHGRNNSEH VEEFLKFYNV DGDSLVEVTN KDDTSLYEVR SARQALADNV
DFLGKPPKRF YEALAHICYR RKRKSSIREV G
//
