ID C4YQZ8_CANAW Unreviewed; 271 AA.
AC C4YQZ8;
DT 05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EEQ46151.1};
GN ORFNames=CAWG_04495 {ECO:0000313|EMBL:EEQ46151.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ46151.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ46151.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ46151.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. BUD23/WBSCR22 family. {ECO:0000256|ARBA:ARBA00005547}.
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DR EMBL; CM000311; EEQ46151.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YQZ8; -.
DR SMR; C4YQZ8; -.
DR PaxDb; 5476-C4YQZ8; -.
DR VEuPathDB; FungiDB:CAWG_04495; -.
DR HOGENOM; CLU_055194_0_2_1; -.
DR OMA; FYPKNDE; -.
DR Proteomes; UP000001429; Chromosome 5.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0016435; F:rRNA (guanine) methyltransferase activity; IEA:InterPro.
DR GO; GO:0070476; P:rRNA (guanine-N7)-methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR039769; Bud23-like.
DR InterPro; IPR022238; Bud23_C.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12734:SF0; 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR12734; METHYLTRANSFERASE-RELATED; 1.
DR Pfam; PF08241; Methyltransf_11; 1.
DR Pfam; PF12589; WBS_methylT; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 54..156
FT /note="Methyltransferase type 11"
FT /evidence="ECO:0000259|Pfam:PF08241"
FT DOMAIN 222..268
FT /note="18S rRNA (guanine(1575)-N(7))-methyltransferase
FT Bud23 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12589"
FT REGION 213..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..265
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 271 AA; 30231 MW; 5668628A1F5E9D9F CRC64;
MSRPEELAPP EVFYNDSESF KYTSSTRVQH IQAKMTLRAL ELLNLEQDSP QFLLDIGCGS
GLSGEILTEE GYNWIGMDIS PSMLATGLDR DVEGDLFLGD VGNGIPFRAG TFDAAISISV
IQWLCNADIS GADPKKRLLN FFNTLYASLK RGGKFVAQFY PKNDVQTENI MGAAKVAGFG
GGLVIDDPES KRHKKYYLVL TAGMADRQIN LSGAEMDAPA EQQTKGLSRK RKKAMESKKD
FINRKKEIMR KRGRKVAEDS KFTGRKRRPR F
//
