ID C4YS75_CANAW Unreviewed; 776 AA.
AC C4YS75;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=CAWG_04934 {ECO:0000313|EMBL:EEQ46578.1};
OS Candida albicans (strain WO-1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294748 {ECO:0000313|EMBL:EEQ46578.1, ECO:0000313|Proteomes:UP000001429};
RN [1] {ECO:0000313|EMBL:EEQ46578.1, ECO:0000313|Proteomes:UP000001429}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WO-1 {ECO:0000313|EMBL:EEQ46578.1,
RC ECO:0000313|Proteomes:UP000001429};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
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DR EMBL; CM000312; EEQ46578.1; -; Genomic_DNA.
DR AlphaFoldDB; C4YS75; -.
DR PaxDb; 5476-C4YS75; -.
DR VEuPathDB; FungiDB:CAWG_04934; -.
DR HOGENOM; CLU_010475_1_0_1; -.
DR OMA; LEGWMRF; -.
DR Proteomes; UP000001429; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22763; RING ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR22763:SF165; TRANSMEMBRANE E3 UBIQUITIN-PROTEIN LIGASE 1; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..776
FT /note="RING-type domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002946864"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 541..563
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 569..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 599..618
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 630..650
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 712..770
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 776 AA; 88960 MW; D74AF55813AEF82F CRC64;
MAIDRQTLVF FIIMFIFLSL PSGNEQPHSD KDRETLQTYQ QSIRNSSSIL QNSTYASGYG
NITGYQLSYK DQLQGKSVAD WPIHEFSPSH PWVESQEYSI LPDEISQRVR KFWGISPVKD
KAYLLNISGR ADGEFQLIES KVKPTKLSIP KYLKEYYKSR ENSFTSDEPT EDNREYFKKP
IDKKGNVTTN EGVVSIAIKG SQYNFDDPKL SRFVGPEDKV DNAICVSMDL NIKDYPEIED
HSLVLNGVYF QETGSLIGVT NSAKFYGNYG LSHLTMGDKN FAIAKTLMTQ FSNMTNDNEL
TMDDMNYGIV KAHEQCEYIA FIQFAKTNFT HERLREIDEE LETPTGRPLP HEIPKIVIEE
YLLYSPDCGK VLSLKPGSVF SGKKTEVTRA QMRNVLTGIL VLVGFQLFLV LRQIKNAQTP
GQLSLISSKT LFLLGYQDSL VAIMTLLLST ITVELYLILA CIATIAFISC GVFEMRFMVS
VLTTQANERG TSWWEILRGA NAEREQQVPE EGPILPIAND PPPQETVPNQ AWQETSYSNS
IFASGFSITI VSMFIIFSSL QWRIQYRKAF EYVSLVFVNS FWVPQFFRNT LKNRRKSFTW
EFAFGTSVIR VLPIYYFALV KGNPLRHRYD PILCIVVSVW LGVQLLLLVL QNQFGPRFWI
NEKWLPKAYE YQRLLSMKDL QEEGFSSELL ENLKTTMSQS EDQDIVTSQC MCPICMTDVD
LPISVKEDKL EEAKRKVNIK GFMITPCHHI FHTECLENWM KYKLQCPVCR KSLPPI
//
