ID C5AYA0_METEA Unreviewed; 435 AA.
AC C5AYA0;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Oxidoreductase (Tat pathway signal) {ECO:0000313|EMBL:ACS41199.1};
DE EC=1.1.99.28 {ECO:0000313|EMBL:ACS41199.1};
GN OrderedLocusNames=MexAM1_META1p3462 {ECO:0000313|EMBL:ACS41199.1};
OS Methylorubrum extorquens (strain ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB
OS 9133 / AM1) (Methylobacterium extorquens).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Methylobacteriaceae; Methylorubrum.
OX NCBI_TaxID=272630 {ECO:0000313|EMBL:ACS41199.1, ECO:0000313|Proteomes:UP000009081};
RN [1] {ECO:0000313|EMBL:ACS41199.1, ECO:0000313|Proteomes:UP000009081}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 14718 / DSM 1338 / JCM 2805 / NCIMB 9133 / AM1
RC {ECO:0000313|Proteomes:UP000009081};
RX PubMed=19440302; DOI=10.1371/journal.pone.0005584;
RA Vuilleumier S., Chistoserdova L., Lee M.-C., Bringel F., Lajus A., Zhou Y.,
RA Gourion B., Barbe V., Chang J., Cruveiller S., Dossat C., Gillett W.,
RA Gruffaz C., Haugen E., Hourcade E., Levy R., Mangenot S., Muller E.,
RA Nadalig T., Pagni M., Penny C., Peyraud R., Robinson D.G., Roche D.,
RA Rouy Z., Saenampechek C., Salvignol G., Vallenet D., Wu Z., Marx C.J.,
RA Vorholt J.A., Olson M.V., Kaul R., Weissenbach J., Medigue C.,
RA Lidstrom M.E.;
RT "Methylobacterium genome sequences: a reference blueprint to investigate
RT microbial metabolism of C1 compounds from natural and industrial sources.";
RL PLoS ONE 4:E5584-E5584(2009).
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family.
CC {ECO:0000256|ARBA:ARBA00010928}.
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DR EMBL; CP001510; ACS41199.1; -; Genomic_DNA.
DR RefSeq; WP_012753277.1; NC_012808.1.
DR AlphaFoldDB; C5AYA0; -.
DR STRING; 272630.MexAM1_META1p3462; -.
DR KEGG; mea:Mex_1p3462; -.
DR eggNOG; COG0673; Bacteria.
DR HOGENOM; CLU_023194_5_1_5; -.
DR OrthoDB; 9774191at2; -.
DR Proteomes; UP000009081; Chromosome.
DR GO; GO:0047061; F:glucose-fructose oxidoreductase activity; IEA:UniProtKB-EC.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR008354; Glc-Fru_OxRdtase_bac.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR22604; OXIDOREDUCTASES; 1.
DR PANTHER; PTHR22604:SF105; TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE; 1.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR PRINTS; PR01775; GLFROXRDTASE.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51318; TAT; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ACS41199.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009081}.
FT DOMAIN 80..203
FT /note="Gfo/Idh/MocA-like oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01408"
FT DOMAIN 220..414
FT /note="Gfo/Idh/MocA-like oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02894"
FT REGION 414..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 435 AA; 46177 MW; 80D364595CF856C3 CRC64;
MSDDPQLSRR LLLAGGAGLT GAALGLGGAA RAASDAPAPS VPADTGAVQG DRIVFPNWRD
AGDVPPPPPP APMPPSQRVG FAIVGLGRLS LEEILPAFGE AKKAKVVALM SGSPDKARIT
AAQYGIPADA IYGYDQWDRL KANPAVKAVY IVTPNGLHRD NVLAAAGAGK HVLCEKPMAN
SSAEAQEMVE ACNRAGVKLM IAYRCQYEPF NREVVRLARS GEFGRVKMVE AFNGQTTALP
EQWRLRKALA GGGALPDIGL YCLNGVRALL GEEPVSIQAQ IVTPENDPRF KEVEESVAFT
LRFPSGVIAQ CGTSYGVHES RSLRVHTTGG SLDLANAFAY RGQRLTIAHR EGSHVQRDEP
VLTHKNQFAL ELDHMAECIL ADRRPRTPGE EGLQDMILME AIYAAARSGQ PVTVGPLAGT
GQGADATRGP ALEEK
//
