ID C5C783_MICLC Unreviewed; 257 AA.
AC C5C783;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Demethylmenaquinone methyltransferase {ECO:0000313|EMBL:SQG48002.1};
DE EC=2.1.1.163 {ECO:0000313|EMBL:SQG48002.1};
DE SubName: Full=Methylase involved in ubiquinone/menaquinone biosynthesis {ECO:0000313|EMBL:ACS31571.1};
GN Name=ubiE_1 {ECO:0000313|EMBL:SQG48002.1};
GN OrderedLocusNames=Mlut_21030 {ECO:0000313|EMBL:ACS31571.1};
GN ORFNames=NCTC2665_00774 {ECO:0000313|EMBL:SQG48002.1};
OS Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 /
OS NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Micrococcus.
OX NCBI_TaxID=465515 {ECO:0000313|EMBL:ACS31571.1, ECO:0000313|Proteomes:UP000000738};
RN [1] {ECO:0000313|EMBL:ACS31571.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NCTC 2665 {ECO:0000313|EMBL:ACS31571.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Lowry S., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Young M., Greenblatt C.;
RT "Complete sequence of Micrococcus luteus NCTC 2665.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000000738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 /
RC NCTC 2665 / VKM Ac-2230 {ECO:0000313|Proteomes:UP000000738};
RX PubMed=19948807; DOI=10.1128/JB.01254-09;
RA Young M., Artsatbanov V., Beller H.R., Chandra G., Chater K.F., Dover L.G.,
RA Goh E.B., Kahan T., Kaprelyants A.S., Kyrpides N., Lapidus A., Lowry S.R.,
RA Lykidis A., Mahillon J., Markowitz V., Mavromatis K., Mukamolova G.V.,
RA Oren A., Rokem J.S., Smith M.C., Young D.I., Greenblatt C.L.;
RT "Genome sequence of the Fleming strain of Micrococcus luteus, a simple
RT free-living actinobacterium.";
RL J. Bacteriol. 192:841-860(2010).
RN [3] {ECO:0000313|EMBL:SQG48002.1, ECO:0000313|Proteomes:UP000248985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC2665 {ECO:0000313|EMBL:SQG48002.1,
RC ECO:0000313|Proteomes:UP000248985};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000256|ARBA:ARBA00008361}.
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DR EMBL; CP001628; ACS31571.1; -; Genomic_DNA.
DR EMBL; LS483396; SQG48002.1; -; Genomic_DNA.
DR RefSeq; WP_010080016.1; NZ_WBMF01000176.1.
DR AlphaFoldDB; C5C783; -.
DR STRING; 465515.Mlut_21030; -.
DR EnsemblBacteria; ACS31571; ACS31571; Mlut_21030.
DR KEGG; mlu:Mlut_21030; -.
DR eggNOG; COG2227; Bacteria.
DR HOGENOM; CLU_069129_7_4_11; -.
DR Proteomes; UP000000738; Chromosome.
DR Proteomes; UP000248985; Chromosome 1.
DR GO; GO:0043770; F:demethylmenaquinone methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102094; F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102955; F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0102027; F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR041698; Methyltransf_25.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR43464:SF102; METHYLTRANSF_25 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43464; METHYLTRANSFERASE; 1.
DR Pfam; PF13649; Methyltransf_25; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:ACS31571.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000738};
KW Transferase {ECO:0000313|EMBL:SQG48002.1};
KW Ubiquinone {ECO:0000313|EMBL:ACS31571.1}.
FT DOMAIN 53..144
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13649"
SQ SEQUENCE 257 AA; 27918 MW; 65D90928C96DE6C2 CRC64;
MTDAPSRAEA NRRTYDDARL AAIYDVDNPA GEDHAFFRRV ADEVSAARAS TRIVDLGCGT
GILTVTLAGP GRDVVGIDPA EAMLAAARAR PGGDGVEWRH GDAGLIAPDS ADLVVMSGNV
AMHLVDDDWH ASLRRIGAGL VPGGRLVFET RNPVRRAWEG WQQDPTERTM PAGRVLESER
TSAPDRHGVV TMRVRTEFLD SGEVSEVDQH LQFRSAEQVR ADLAAAGLRV ERLSGDWHRT
AFDPAEHPLM VVEAVRD
//
