ID C5C8F1_MICLC Unreviewed; 607 AA.
AC C5C8F1;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Glycosidase {ECO:0000313|EMBL:ACS29753.1};
DE SubName: Full=Trehalose-6-phosphate hydrolase {ECO:0000313|EMBL:SQG48528.1};
DE EC=3.2.1.93 {ECO:0000313|EMBL:SQG48528.1};
GN Name=treA {ECO:0000313|EMBL:SQG48528.1};
GN OrderedLocusNames=Mlut_01920 {ECO:0000313|EMBL:ACS29753.1};
GN ORFNames=NCTC2665_01209 {ECO:0000313|EMBL:SQG48528.1};
OS Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 /
OS NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Micrococcus.
OX NCBI_TaxID=465515 {ECO:0000313|EMBL:ACS29753.1, ECO:0000313|Proteomes:UP000000738};
RN [1] {ECO:0000313|EMBL:ACS29753.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NCTC 2665 {ECO:0000313|EMBL:ACS29753.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Lowry S., Larimer F., Land M., Hauser L.,
RA Kyrpides N., Lykidis A., Young M., Greenblatt C.;
RT "Complete sequence of Micrococcus luteus NCTC 2665.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000000738}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 /
RC NCTC 2665 / VKM Ac-2230 {ECO:0000313|Proteomes:UP000000738};
RX PubMed=19948807; DOI=10.1128/JB.01254-09;
RA Young M., Artsatbanov V., Beller H.R., Chandra G., Chater K.F., Dover L.G.,
RA Goh E.B., Kahan T., Kaprelyants A.S., Kyrpides N., Lapidus A., Lowry S.R.,
RA Lykidis A., Mahillon J., Markowitz V., Mavromatis K., Mukamolova G.V.,
RA Oren A., Rokem J.S., Smith M.C., Young D.I., Greenblatt C.L.;
RT "Genome sequence of the Fleming strain of Micrococcus luteus, a simple
RT free-living actinobacterium.";
RL J. Bacteriol. 192:841-860(2010).
RN [3] {ECO:0000313|EMBL:SQG48528.1, ECO:0000313|Proteomes:UP000248985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC2665 {ECO:0000313|EMBL:SQG48528.1,
RC ECO:0000313|Proteomes:UP000248985};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001628; ACS29753.1; -; Genomic_DNA.
DR EMBL; LS483396; SQG48528.1; -; Genomic_DNA.
DR RefSeq; WP_010079611.1; NZ_WBMF01000063.1.
DR AlphaFoldDB; C5C8F1; -.
DR STRING; 465515.Mlut_01920; -.
DR CAZy; GH13; Glycoside Hydrolase Family 13.
DR EnsemblBacteria; ACS29753; ACS29753; Mlut_01920.
DR KEGG; mlu:Mlut_01920; -.
DR PATRIC; fig|465515.4.peg.168; -.
DR eggNOG; COG0366; Bacteria.
DR HOGENOM; CLU_006462_0_1_11; -.
DR Proteomes; UP000000738; Chromosome.
DR Proteomes; UP000248985; Chromosome 1.
DR GO; GO:0008788; F:alpha,alpha-phosphotrehalase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd11332; AmyAc_OligoGlu_TS; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR045857; O16G_dom_2.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF179; NEUTRAL AND BASIC AMINO ACID TRANSPORT PROTEIN RBAT; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:ACS29753.1};
KW Hydrolase {ECO:0000313|EMBL:SQG48528.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000738}.
FT DOMAIN 29..448
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
SQ SEQUENCE 607 AA; 67172 MW; 8A8F07902D700C09 CRC64;
MTTQRLSTPP SEARNRPVTP WWVDAVIYQV YPRSFADADG DGMGDLRGVT SRLDYLAQLG
VDAIWLSPFY LSPQHDAGYD VADYRTVDPR FGTLADADEM IAAAHEAGIR VVVDLVPNHT
SSEHAWFQAA LAAGPGSPER ARYHFAEGRG EHGELPPNNW ESTFGGGAWT RVTEADGTPG
QWYLHLFDTT QPDLNWENEE VREEFRSILR FWLDRGVDGF RVDVAHGLIK QPGYPDAEHS
RMGMVTDAGE DADPTFDPDT FEPLTPFMDQ DRVHEVYRDW RRVLDSYDHE PMMVAEAWVA
PLSRMFRYVR PGEMHQTFNF TYLMAGWDAV SLTHAIDRSF EQADRVGAPN TWVLSNHDTV
RHASRYGLAD PSSYPAGITA EDEQPDEAVG RRRARAAAMV ELGLPGSAYI YQGDELGLPE
HTTLAAEHRQ DPYFFRTDGK EPGRDGCRIP LPWAADEPSY GFSTPADDDS PASAAEGVAA
PWLPQPASFR ALAADRQVGV EGSVFELYRR LLQIRGELDL GTGTFAWSEH HDPARGVLAF
TVTSGGGRHL GSGEPIPART VLVMANLSTD PVDLPAGHSR ALFSLEEAEA VQDGQLAHDA
AAWLLMD
//
