ID C5CLY6_VARPS Unreviewed; 659 AA.
AC C5CLY6;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Proprionate catabolism activator, Fis family {ECO:0000313|EMBL:ACS19393.1};
GN OrderedLocusNames=Vapar_2771 {ECO:0000313|EMBL:ACS19393.1};
OS Variovorax paradoxus (strain S110).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=543728 {ECO:0000313|EMBL:ACS19393.1};
RN [1] {ECO:0000313|EMBL:ACS19393.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S110 {ECO:0000313|EMBL:ACS19393.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Orwin P.,
RA Leadbetter J.R., Spain J.C., Han J.I.;
RT "Complete sequence of chromosome 1 of Variovorax paradoxus S110.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001635; ACS19393.1; -; Genomic_DNA.
DR AlphaFoldDB; C5CLY6; -.
DR STRING; 543728.Vapar_2771; -.
DR KEGG; vap:Vapar_2771; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_8_5_4; -.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR Gene3D; 3.40.50.10660; PrpR receptor domain-like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR012704; Sig_transdc_resp-reg_PrpR.
DR InterPro; IPR010524; Sig_transdc_resp-reg_PrpR_N.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR02329; propionate_PrpR; 1.
DR PANTHER; PTHR32071:SF21; PROPIONATE CATABOLISM OPERON REGULATORY PROTEIN; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF06506; PrpR_N; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF159800; PrpR receptor domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 216..269
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 345..577
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 659 AA; 73058 MW; AC0964FEB6F22698 CRC64;
MFQCDMPSDR PSSHFFPAPV RSGELPRLCF LSYRQIRGFA MPVVAEYTGR AEIEVVDGTF
GDALAIARDR LERGLVDAFV SAGSNASILR AGLQAPVGTI QLSGFDLLQA LIKARRMSSR
VGVVMYGQTI PELDEVKDLL NIEVVQHAYQ TPDDARQRFE QLRREGFEVI VGSSLVVELA
EQAGLHGLLA YSLGSVRKGF EDALELARVA RLEAGRYEQL NGVLHNLQEA VLAVNRDNRV
IAVNPPMQQL LGPPHARLIG QSLEAIEPEL SLQPTLDSGQ VERAVVQRFA QRDWVVNRTP
IREHGEIVGA ALTLYDARTI QEADTSLRIQ QGRRQSAARH RFANLIGQSP AFLRAVQTAR
RFARTDLTVL IAGESGVGKE LFAQSIHNES VRAGRPFVAV NCAAFPEALL ESELFGYEEG
AFTGSRRGGK RGLFEAAHTG TLFLDEIGDM PLQLQTRLLR VLQEREITRL GATAAIPVDV
RVIAATHQPL NDMIAERRFR QDLFYRLNTL RLPLPPLRER REDIAPLAEA QVGRCLQRLG
TRLDPVRALA PLLPRLRAYD WPGNIRELEN LGERIAVFLM QFDHLEDVRY DELRHDLPEL
FADTAASEVA DDTGLSAARV AAALQAQGGN RQAAARQLGV SRSTLWRWMR ERGADAPGS
//
