ID C5CU45_VARPS Unreviewed; 373 AA.
AC C5CU45;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Methionine synthase vitamin-B12 independent {ECO:0000313|EMBL:ACS18395.1};
GN OrderedLocusNames=Vapar_1745 {ECO:0000313|EMBL:ACS18395.1};
OS Variovorax paradoxus (strain S110).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=543728 {ECO:0000313|EMBL:ACS18395.1};
RN [1] {ECO:0000313|EMBL:ACS18395.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=S110 {ECO:0000313|EMBL:ACS18395.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Orwin P.,
RA Leadbetter J.R., Spain J.C., Han J.I.;
RT "Complete sequence of chromosome 1 of Variovorax paradoxus S110.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001635; ACS18395.1; -; Genomic_DNA.
DR AlphaFoldDB; C5CU45; -.
DR STRING; 543728.Vapar_1745; -.
DR KEGG; vap:Vapar_1745; -.
DR eggNOG; COG0620; Bacteria.
DR HOGENOM; CLU_058877_0_0_4; -.
DR OrthoDB; 6430685at2; -.
DR GO; GO:0003871; F:5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009086; P:methionine biosynthetic process; IEA:InterPro.
DR CDD; cd03311; CIMS_C_terminal_like; 1.
DR Gene3D; 3.20.20.210; -; 1.
DR InterPro; IPR002629; Met_Synth_C/arc.
DR InterPro; IPR038071; UROD/MetE-like_sf.
DR PANTHER; PTHR43844; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR43844:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF01717; Meth_synt_2; 1.
DR SUPFAM; SSF51726; UROD/MetE-like; 1.
PE 4: Predicted;
FT DOMAIN 14..367
FT /note="Cobalamin-independent methionine synthase MetE C-
FT terminal/archaeal"
FT /evidence="ECO:0000259|Pfam:PF01717"
SQ SEQUENCE 373 AA; 41863 MW; 865E601C6392578B CRC64;
MSQHAALPAR YDHVGSFLRP KYLLEAREQK AKGEITPEQL RKVEDKAITE IVRFQEDIGL
KSITDGEFRR TYFHIDFLDQ LGGVKTDIPV TIRKPDGTEE LAPPAMRVLD KVRHIKDIQL
ADFQYLKSQV SAGRTPKVTI PSPTMLHFRG GRAGISKEAY PELDPVFYDD VAKAYGDELR
SLAAAGCTYV QMDDTNLAYL CDEHMREAAR KRGDDPNELP HRYAAFINKV VAQKPPGMLL
AMHLCRGNFK STHAAAGNYE PVAEALLKEM DLDAYFMEYD DARSGDFKPL RYLPKGKTVV
LGLVTTKFGE MEDKDELKRR IEDAAKYAPL EQLALSPQCG FSSTVHGNNI AVEAQRAKLR
LVVETAQEVW GST
//
