ID C5DDS2_LACTC Unreviewed; 467 AA.
AC C5DDS2;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE RecName: Full=Glycosidase {ECO:0000256|PIRNR:PIRNR037299};
DE EC=3.2.-.- {ECO:0000256|PIRNR:PIRNR037299};
GN OrderedLocusNames=KLTH0C03344g {ECO:0000313|EMBL:CAR21933.1};
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR21933.1, ECO:0000313|Proteomes:UP000002036};
RN [1] {ECO:0000313|EMBL:CAR21933.1, ECO:0000313|Proteomes:UP000002036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC {ECO:0000313|Proteomes:UP000002036};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 16 family.
CC {ECO:0000256|PIRNR:PIRNR037299}.
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DR EMBL; CU928167; CAR21933.1; -; Genomic_DNA.
DR RefSeq; XP_002552371.1; XM_002552325.1.
DR AlphaFoldDB; C5DDS2; -.
DR STRING; 559295.C5DDS2; -.
DR GeneID; 8291235; -.
DR KEGG; lth:KLTH0C03344g; -.
DR eggNOG; ENOG502QVQI; Eukaryota.
DR HOGENOM; CLU_040459_0_0_1; -.
DR InParanoid; C5DDS2; -.
DR OMA; WNATANQ; -.
DR OrthoDB; 337487at2759; -.
DR Proteomes; UP000002036; Chromosome C.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:UniProtKB-UniRule.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0031505; P:fungal-type cell wall organization; IEA:UniProt.
DR CDD; cd06923; ChtBD1_GH16; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000757; GH16.
DR InterPro; IPR017168; Glyco_hydro_16_CRH1_prd.
DR PANTHER; PTHR10963:SF22; GLYCOSIDASE CRH2-RELATED; 1.
DR PANTHER; PTHR10963; GLYCOSYL HYDROLASE-RELATED; 1.
DR Pfam; PF00722; Glyco_hydro_16; 1.
DR PIRSF; PIRSF037299; Glycosidase_CRH1_prd; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51762; GH16_2; 1.
PE 3: Inferred from homology;
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Hydrolase {ECO:0000256|PIRNR:PIRNR037299};
KW Membrane {ECO:0000256|PIRNR:PIRNR037299};
KW Reference proteome {ECO:0000313|Proteomes:UP000002036};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..467
FT /note="Glycosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002947794"
FT DOMAIN 67..299
FT /note="GH16"
FT /evidence="ECO:0000259|PROSITE:PS51762"
FT REGION 343..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 170
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR037299-1"
FT ACT_SITE 174
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR037299-1"
SQ SEQUENCE 467 AA; 49866 MW; 50A61747606CA193 CRC64;
MAGSKLFFLS AISALTSVVA AATTEKVVYC NETLAACPED KPCCSQYGVC GSGSYCLGGC
NPRYSHNITA CMPMPVCKDF QTVFSNYSGD LQSQYTYLGD AEKHDWIYEG YTMDYDKEDA
LVLAMPKNSG GTVLSSTRYV WYGKVGARLK TSHDAGVVTA FIMFSSVQDE IDYEYVGNNL
TQVQTNYYFE GVQNWTHSTN VSTTDTFDNY HLYEVDWHED HIDWLIDGEV SRTLLKNSTF
NATSGEYMFP QTPARIQISI WPGGNATNPV GTRSWAGGEI NWDSSDIQDY GYYYALLQGV
NVTCYDPPAG TVKNGSVSYE YISSENFTQN YVAITNGTTV MGSADDTGYN PEDGKSSSSS
SSSSSSSPAA SKSTQKGSSS TDKSSSTESG LKVATGSSSV SSAKQSGFVQ NINSASSSAT
GKSSATSTGS SATSTGGAAG LSYAPISNNG LMHIAMGLFG AAFAFLY
//
