ID C5DQJ7_ZYGRC Unreviewed; 926 AA.
AC C5DQJ7;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 28-JUN-2023, entry version 60.
DE RecName: Full=Nitrogen permease regulator 3 {ECO:0000256|RuleBase:RU368069};
DE AltName: Full=Required for meiotic nuclear division protein 11 {ECO:0000256|RuleBase:RU368069};
GN OrderedLocusNames=ZYRO0B00902g {ECO:0000313|EMBL:CAR26058.1};
OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS / NRRL Y-229) (Candida mogii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX NCBI_TaxID=559307 {ECO:0000313|EMBL:CAR26058.1, ECO:0000313|Proteomes:UP000008536};
RN [1] {ECO:0000313|Proteomes:UP000008536}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC Y-229 {ECO:0000313|Proteomes:UP000008536};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC amino acid starvation. Required for meiotic nuclear division.
CC {ECO:0000256|RuleBase:RU368069}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000256|RuleBase:RU368069};
CC Peripheral membrane protein {ECO:0000256|RuleBase:RU368069}.
CC -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000256|ARBA:ARBA00010546,
CC ECO:0000256|RuleBase:RU368069}.
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DR EMBL; CU928174; CAR26058.1; -; Genomic_DNA.
DR RefSeq; XP_002494991.1; XM_002494946.1.
DR AlphaFoldDB; C5DQJ7; -.
DR STRING; 559307.C5DQJ7; -.
DR GeneID; 8202130; -.
DR KEGG; zro:ZYRO0B00902g; -.
DR HOGENOM; CLU_014314_0_0_1; -.
DR InParanoid; C5DQJ7; -.
DR Proteomes; UP000008536; Chromosome B.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-UniRule.
DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR InterPro; IPR005365; Npr3.
DR PANTHER; PTHR13153; CGTHBA PROTEIN -14 GENE PROTEIN; 1.
DR PANTHER; PTHR13153:SF5; GATOR COMPLEX PROTEIN NPRL3; 1.
DR Pfam; PF03666; NPR3; 1.
PE 3: Inferred from homology;
KW Meiosis {ECO:0000256|RuleBase:RU368069};
KW Reference proteome {ECO:0000313|Proteomes:UP000008536};
KW Signal {ECO:0000256|RuleBase:RU368069}.
FT REGION 35..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 323..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..834
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 37..53
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..127
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 323..338
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..380
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 105018 MW; 7957DF656173344F CRC64;
MHELLPNSCL LGIHLTISTH SGPQVVYHYP PASEDYISGK QRQSRQDSTG VDDGESNGKI
YAGNLRKKPS MGASLTGQSL FSSDQKFNDE DNIKTPSIRS GGTGSIRRRR THSIDSGKVR
HGVETESASS DTDPSSSGLS DSELSTDYAD ESSDSSSSLE NERNDEPEDI SNEPRLSNSV
TRNNTSANTT NLEPTRMLRP KSSQVSASKL LDIFNKEGPD RRPSAISKIS NTRTPESSED
EADDDQKSEL DFSELHERGK IMLDKQYFAE NVFQDINKIF GLDAEFVAEF CSPEREMCNT
RYEFTVDTLC FLGLPVHVDQ HGNWRKSKRK KHTTRSKRSS STTTRLSKQR SSLSQNGDGE
SGENDMDSSQ LRSSSHNLQD DNGEINEDND ECENSNNQNI KEDLEKNMNM FHVCFVMNPS
LVEYNERIDD MFHYAVARLS MLLRYAQEKS QYVSKECSII MKEKEHVLKH SKTYRAIKGA
NQRGKYLYQC ILSKSSLARA LTLCVEKLQQ NDIACLEIGE DKVIALQIPI QNEFAVLPNF
KLHPVLRGSF LSSVLNSQFL SAGPLAKEES LGGYTDSDHE DLTDLLNFAL LLDEPTNIIK
ELETFSYHDD IGNIVLSHIV KHIQPNVPLG SYQYLIDELF GDTSDDVRGS FQTNMLRSCA
LHLLYRRHAR LIIPISSRNT YIVSPLAPIR GYSKNDYDGL QNSSMPLIYQ NQTIFKERFP
TLPSLPSFLH LLSNGKPKPY GNIIPSKEHK SIYLGALAWL LKYGYVTQLL TFVCIRVDRQ
IKMAVDEDLE KEGFKAKTHS VDRDHDAMDN VAKNAKDLQT SQKNRTSSNE EEEEDIARFA
YDDPDIGRDY TIILEPERAT AIEKRWMFKC VQDQPTDIQK LFGKLLKYFN GRTPMELIIL
KEGISRHDIR KLIGTLDRYV IEFDHW
//
