ID C5E2V4_LACTC Unreviewed; 447 AA.
AC C5E2V4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=Rab GDP dissociation inhibitor {ECO:0000256|RuleBase:RU363124};
GN OrderedLocusNames=KLTH0H07986g {ECO:0000313|EMBL:CAR30365.1};
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295 {ECO:0000313|EMBL:CAR30365.1, ECO:0000313|Proteomes:UP000002036};
RN [1] {ECO:0000313|EMBL:CAR30365.1, ECO:0000313|Proteomes:UP000002036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284
RC {ECO:0000313|Proteomes:UP000002036};
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- SIMILARITY: Belongs to the Rab GDI family.
CC {ECO:0000256|ARBA:ARBA00005593, ECO:0000256|RuleBase:RU363124}.
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DR EMBL; CU928180; CAR30365.1; -; Genomic_DNA.
DR RefSeq; XP_002556227.1; XM_002556181.1.
DR AlphaFoldDB; C5E2V4; -.
DR STRING; 559295.C5E2V4; -.
DR GeneID; 8294545; -.
DR KEGG; lth:KLTH0H07986g; -.
DR eggNOG; KOG1439; Eukaryota.
DR HOGENOM; CLU_021695_0_0_1; -.
DR InParanoid; C5E2V4; -.
DR OMA; FETKAKM; -.
DR OrthoDB; 8704at2759; -.
DR Proteomes; UP000002036; Chromosome H.
DR GO; GO:0005093; F:Rab GDP-dissociation inhibitor activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.10.405.10; Guanine Nucleotide Dissociation Inhibitor, domain 1; 1.
DR Gene3D; 3.30.519.10; Guanine Nucleotide Dissociation Inhibitor, domain 2; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR018203; GDP_dissociation_inhibitor.
DR InterPro; IPR000806; RabGDI.
DR PANTHER; PTHR11787:SF8; RAB GDP DISSOCIATION INHIBITOR; 1.
DR PANTHER; PTHR11787; RAB GDP-DISSOCIATION INHIBITOR; 1.
DR Pfam; PF00996; GDI; 1.
DR PRINTS; PR00892; RABGDI.
DR PRINTS; PR00891; RABGDIREP.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002036}.
SQ SEQUENCE 447 AA; 50502 MW; DE8D4445773DB09E CRC64;
MDESYDVIVL GTGLTECILS GLLSVDGKKV LHIDKQDHYG GESASVALSQ LYQKFKQNPI
PKDQMEAKFG RDRDWSVDLI PKFLMADGGL TKILVHTDVT RYIDFKQVAG SYVYNKGKIY
KVPSNEMEAI SSPLMGIFEK RRMKRFMEWI SEYQEDDVKT HQGLDLDKNT MDEVYYKFGL
GTSTKDFIGH SMALWTNDDY LQEPARPTFE RILLYVQSVA RYGKSPYLYP LYGLGELPQG
FARLSAIYGG TYMLNTPVEK VLYDDDGKFQ GVVTKEGTAK APLVIADPTY FPEKCKSTGQ
KVIRAICILN HPVPNTSNAD SLQIIIPQSQ VGRKNDIYVA VMSDSHNVAS KGFYLAIVST
IIETDTPHVE LEPAFKLLGP IEERFMGIAE IFEPKESGST DNVFLSRSYD SSSHFESMTD
DVKDIYFRVT GHPLVLKKRP QEEEEEE
//
