ID C5E9G4_BIFLI Unreviewed; 499 AA.
AC C5E9G4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Acyl-CoA reductase {ECO:0000256|PIRNR:PIRNR009414};
DE EC=1.2.1.50 {ECO:0000256|PIRNR:PIRNR009414};
GN ORFNames=BLIG_00524 {ECO:0000313|EMBL:EEQ54573.1};
OS Bifidobacterium longum subsp. infantis CCUG 52486.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=537937 {ECO:0000313|EMBL:EEQ54573.1};
RN [1] {ECO:0000313|EMBL:EEQ54573.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 52486 {ECO:0000313|EMBL:EEQ54573.1};
RG The Broad Institute Genome Sequencing Platform;
RA Gougoulias C., Tuohy K.M., Gibson G.R., Ward D., Mehta T., Young S.,
RA Jaffe D., Gnerre S., Berlin A., Heiman D., Hepburn T., Shea T., Sykes S.,
RA Alvarado L., Kodira C., Borodovsky M., Lander E., Galagan J., Nusbaum C.,
RA Birren B.;
RT "Annotation of Bifidobacterium longum subsp. infantis CCUG 52486.";
RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a long-chain fatty aldehyde + CoA + NADP(+) = a long-chain
CC fatty acyl-CoA + H(+) + NADPH; Xref=Rhea:RHEA:15437,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:17176, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:83139; EC=1.2.1.50;
CC Evidence={ECO:0000256|PIRNR:PIRNR009414};
CC -!- SIMILARITY: Belongs to the LuxC family.
CC {ECO:0000256|PIRNR:PIRNR009414}.
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DR EMBL; DS990238; EEQ54573.1; -; Genomic_DNA.
DR RefSeq; WP_007051634.1; NZ_DS990238.1.
DR AlphaFoldDB; C5E9G4; -.
DR HOGENOM; CLU_043373_0_0_11; -.
DR Proteomes; UP000005084; Unassembled WGS sequence.
DR GO; GO:0003995; F:acyl-CoA dehydrogenase activity; IEA:InterPro.
DR GO; GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0008218; P:bioluminescence; IEA:InterPro.
DR CDD; cd07080; ALDH_Acyl-CoA-Red_LuxC; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR008670; CoA_reduct_LuxC.
DR Pfam; PF05893; LuxC; 1.
DR PIRSF; PIRSF009414; LuxC; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
PE 3: Inferred from homology;
KW NADP {ECO:0000256|PIRNR:PIRNR009414};
KW Oxidoreductase {ECO:0000256|PIRNR:PIRNR009414}.
SQ SEQUENCE 499 AA; 54231 MW; AAE3936B0FD8940B CRC64;
MPTVDESVSQ AIDVFHLPSG VDVSDYEIYE VATSDGVKRL RYPRLDGSKV TSLAKQLVDV
RNRTLAAMSV NDILDIVADA AQLWADPDFE LRRQAELLIP AITGYEPDMV RIELKRYMRQ
FRRRELLRFL DSEIGQPSML DEFRPNKAGG YSKYVGPALT YQVFSSNVPG IPVWSMAMTL
LVKGAILGKS SFSEPVMPAF FARSIAMVNS DLADAIAVVP WKGGSQQLED SAIDAADAVI
VYGSSQTTKL IAGKVAGSKP CLGYGAKVGL AFIGREALRP DTYADTVHRV AVDIATYDQQ
SCLAPQTVFV ETDGALTPRE VAQLLGGELE NQQRKYPRSV LSDAENVAIQ RARTDAEMRA
LMGGKAAVFA SGHSTAWSVL YRELDGSGAD EDVASLMSPL NRTVNVVAVP DLLDAARRLT
SCRGWLQSCG VAVDSTRLFG LAGTLAEVGV NRICPLGEMD RAKSGWHHDG GFNLIDLLRA
VDVERGSDAY SDSFDMDME
//
