ID C5L174_PERM5 Unreviewed; 680 AA.
AC C5L174;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Splicing factor U2AF 65 kDa subunit, putative {ECO:0000313|EMBL:EER09481.1};
GN ORFNames=Pmar_PMAR016412 {ECO:0000313|EMBL:EER09481.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER09481.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG678232; EER09481.1; -; Genomic_DNA.
DR RefSeq; XP_002777665.1; XM_002777619.1.
DR AlphaFoldDB; C5L174; -.
DR EnsemblProtists; EER09481; EER09481; Pmar_PMAR016412.
DR GeneID; 9052377; -.
DR InParanoid; C5L174; -.
DR OMA; YGERHGE; -.
DR OrthoDB; 101932at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProt.
DR CDD; cd12230; RRM1_U2AF65; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR PANTHER; PTHR23139; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR23139:SF9; SPLICING FACTOR U2AF 65 KDA SUBUNIT; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 242..327
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 1..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..558
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..680
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..180
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..198
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 520..545
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..643
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 644..664
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 76427 MW; B4944A6A2A2AABA3 CRC64;
MGTSRERSRD DRSSEGRNPR DDSRRRQGGS DRHRSGHKSD DDEGSPKRSR RRNESITRGH
DEQGDDDGRK DKQRHTRDED SGDGSNRKRR RDDKEDEDRK DNRKDYDRIT RRSSRDDRAS
RRKRSRSRDR RDDRRDDRRE GYHHHQHRHH DHYRHDSRER SRRRSPSRRR ERRPRDRGKG
RRWSRSPSEK RKPFKFDSPP KELAAQLAAG TSMLPQTVVS SSSTIKEAFN ATLAAERQKI
ARELYIGQIP PGISAAELID VLNDGLMNMG ANAMPGRPIV HGWLGGDGLF AFVEFRTPEE
ASIALERLNG HQLKSYGVSI KVGRPKGYMG PAAPDDSVNA YTAGHAATSS TTPGGISAAE
VSSDTSRLCL IGFPLKASEH SIKRALRNAS KGEIRHLELL KHTWNDEEIV MAVFECVNIE
DEHRLKKKGE VEVQGVKARI INPKDAIVKG YMNFDGDIMK KAMGLEIVPS RILVMTNFAG
SVEELLDDIN YSDLMDDIKV ECKSITAGAD VRSIIIPRPE STMQPANGND VDTPVGQQPP
NGDINHHDSA TMEDDAGDQR RNTAAVPAVD MQVPGLGCCF IEFRNVEEAG QTRFKRGDFA
NPMPNTDEPE VGLKDIGMNA PLLDDGMDTS DNEEEEGMGD ATNRDDDEEN RMNVLDDAKA
RKKGKQPSPS LAAEDLEIID
//
