ID C5LC25_PERM5 Unreviewed; 433 AA.
AC C5LC25;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=adenosine kinase {ECO:0000256|ARBA:ARBA00012119};
DE EC=2.7.1.20 {ECO:0000256|ARBA:ARBA00012119};
GN ORFNames=Pmar_PMAR011533 {ECO:0000313|EMBL:EER05508.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER05508.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- PATHWAY: Purine metabolism; AMP biosynthesis via salvage pathway; AMP
CC from adenosine: step 1/1. {ECO:0000256|ARBA:ARBA00004801}.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688}.
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DR EMBL; GG680918; EER05508.1; -; Genomic_DNA.
DR RefSeq; XP_002773692.1; XM_002773646.1.
DR AlphaFoldDB; C5LC25; -.
DR EnsemblProtists; EER05508; EER05508; Pmar_PMAR011533.
DR GeneID; 9042031; -.
DR InParanoid; C5LC25; -.
DR OMA; NTARTMK; -.
DR OrthoDB; 5475204at2759; -.
DR UniPathway; UPA00588; UER00659.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0004001; F:adenosine kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0006166; P:purine ribonucleoside salvage; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1110.10; -; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR001805; Adenokinase.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR45769; ADENOSINE KINASE; 1.
DR PANTHER; PTHR45769:SF3; ADENOSINE KINASE; 1.
DR Pfam; PF00294; PfkB; 2.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EER05508.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Purine salvage {ECO:0000256|ARBA:ARBA00022726};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 94..193
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
FT DOMAIN 260..360
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 433 AA; 46770 MW; 7C8B589EB5EFD5A8 CRC64;
MAVNASSSGP ALTGVVSCAD DSLSMCDESR QCEVGLPSTM HSSIVGMCHP LLDLVANIDD
FEAYGLEPAT QRLAKGSDED KKLFARMLGD GELTVHRIAG GQAMNSLRGV KWWFDRHEAD
PEYNDLSFAN TSVRIVGSVG DDEYANVLRE ACAEAGLETD FEVFPGGRTG KCCALLKDKK
RTMITDLGVA PDFRAGPDRG IPADCRVLYT TAFYACGDGY ACREYIPNHP QITSGYTKLF
AGLSAAWACR NDDFTYMAQH ACDVVFGNEV EFTAFAEHLG IAGISKMSPR EIAEAVSAFM
KPGAWAIMTQ GPDPVICCSN LTDTCDAFAH TVRDLDPLAI SDDIGAGDGF VGGFIAAIYA
RLLARDLTPR SIPSPLESSV SSISDDDVSE VLPYEGDRAN AWHSITRQMI MDGVEEGIYC
ARQVMKHTGC QYF
//
