ID C5LJH8_PERM5 Unreviewed; 525 AA.
AC C5LJH8;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN ORFNames=Pmar_PMAR023219 {ECO:0000313|EMBL:EER03107.1};
OS Perkinsus marinus (strain ATCC 50983 / TXsc).
OC Eukaryota; Sar; Alveolata; Perkinsozoa; Perkinsea; Perkinsida; Perkinsidae;
OC Perkinsus.
OX NCBI_TaxID=423536 {ECO:0000313|Proteomes:UP000007800};
RN [1] {ECO:0000313|EMBL:EER03107.1, ECO:0000313|Proteomes:UP000007800}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50983 / TXsc {ECO:0000313|Proteomes:UP000007800};
RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.;
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU004273};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC {ECO:0000256|ARBA:ARBA00008294, ECO:0000256|RuleBase:RU004273}.
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DR EMBL; GG682453; EER03107.1; -; Genomic_DNA.
DR RefSeq; XP_002771291.1; XM_002771245.1.
DR AlphaFoldDB; C5LJH8; -.
DR EnsemblProtists; EER03107; EER03107; Pmar_PMAR023219.
DR GeneID; 9051850; -.
DR InParanoid; C5LJH8; -.
DR OrthoDB; 176705at2759; -.
DR Proteomes; UP000007800; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR CDD; cd00051; EFh; 1.
DR CDD; cd07414; MPP_PP1_PPKL; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR InterPro; IPR031675; STPPase_N.
DR PANTHER; PTHR11668; SERINE/THREONINE PROTEIN PHOSPHATASE; 1.
DR PANTHER; PTHR11668:SF385; SERINE_THREONINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF16891; STPPase_N; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00054; EFh; 1.
DR SMART; SM00156; PP2Ac; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004273};
KW Protein phosphatase {ECO:0000256|ARBA:ARBA00022912};
KW Reference proteome {ECO:0000313|Proteomes:UP000007800}.
FT DOMAIN 400..435
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 525 AA; 58691 MW; 4A6BB8BCAAA0A26B CRC64;
MASPGASTVE SIDVDAIIEK LLEVRGCRPG KGVQLSDGEI RALCNKSRQI FLEQPNLLEL
EAPIKICGDV HGQYYDLLRL FEYGGFPPEA NYLFLGDYVD RGKQSLETIC LLLAYKIKYP
ENFFLLRGNH ECASINRIYG FYDECKRRYN IKLWKIFTDC FNCLPVAAIV DEKILCMHGG
LSPELNSMDQ IKRILRPTDV PDTGLLCDLL WSDPEQDISG WGENDRGVSF TFGADIVQAC
LRKHDLDLIC RAHQVVEDGY EFFAKRQLVT LFSAPNYCGE FDNAGAMMSV DETLMCSFQV
LKPVEKKKKF PTLSELGYDY VLEDSNGISD KEIGELAREF RVVNVIGDGF VTSEEARIAS
SRAGFWSTDD EFADVNSLCY DTPGKVADSR LVSLLRRSAI TELEVVEAFR SFDRDGRGKL
DAADLVNAMT SMGNALLEDE AYQMIHQADP TASGSSERRL TTKLSLALFS VTTGISSEDR
AVYDFVQGVK GCFVGENKKE IKKVFTRARV SQSGECLAKN KTSYV
//
