ID C5MIY4_CANTT Unreviewed; 254 AA.
AC C5MIY4;
DT 28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT 28-JUL-2009, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Manganese/iron superoxide dismutase C-terminal domain-containing protein {ECO:0000259|Pfam:PF02777};
GN ORFNames=CTRG_06027 {ECO:0000313|EMBL:EER30243.1};
OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=294747 {ECO:0000313|EMBL:EER30243.1, ECO:0000313|Proteomes:UP000002037};
RN [1] {ECO:0000313|EMBL:EER30243.1, ECO:0000313|Proteomes:UP000002037}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-3404 / T1 {ECO:0000313|Proteomes:UP000002037};
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W., Harris D., Hoyer L.L., Hube B., Klis F.M.,
RA Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M., Nikolaou E.,
RA Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F., Sherlock G.,
RA Shah P., Silverstein K.A., Skrzypek M.S., Soll D., Staggs R.,
RA Stansfield I., Stumpf M.P., Sudbery P.E., Srikantha T., Zeng Q., Berman J.,
RA Berriman M., Heitman J., Gow N.A., Lorenz M.C., Birren B.W., Kellis M.,
RA Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
CC -!- FUNCTION: Component of the mitochondrial ribosome (mitoribosome), a
CC dedicated translation machinery responsible for the synthesis of
CC mitochondrial genome-encoded proteins, including at least some of the
CC essential transmembrane subunits of the mitochondrial respiratory
CC chain. The mitoribosomes are attached to the mitochondrial inner
CC membrane and translation products are cotranslationally integrated into
CC the membrane. {ECO:0000256|ARBA:ARBA00037226}.
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DR EMBL; GG692405; EER30243.1; -; Genomic_DNA.
DR RefSeq; XP_002546549.1; XM_002546503.1.
DR AlphaFoldDB; C5MIY4; -.
DR STRING; 294747.C5MIY4; -.
DR EnsemblFungi; CTRG_06027-t43_1; CTRG_06027-t43_1-p1; CTRG_06027.
DR GeneID; 8298598; -.
DR KEGG; ctp:CTRG_06027; -.
DR VEuPathDB; FungiDB:CTRG_06027; -.
DR eggNOG; KOG0876; Eukaryota.
DR HOGENOM; CLU_057349_1_1_1; -.
DR OrthoDB; 2055478at2759; -.
DR Proteomes; UP000002037; Unassembled WGS sequence.
DR GO; GO:0005763; C:mitochondrial small ribosomal subunit; IEA:EnsemblFungi.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:EnsemblFungi.
DR GO; GO:0004784; F:superoxide dismutase activity; IEA:InterPro.
DR Gene3D; 3.55.40.20; Iron/manganese superoxide dismutase, C-terminal domain; 1.
DR InterPro; IPR019832; Mn/Fe_SOD_C.
DR InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR InterPro; IPR036314; SOD_C_sf.
DR PANTHER; PTHR43595; 37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43595:SF2; 37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL; 1.
DR Pfam; PF02777; Sod_Fe_C; 2.
DR SUPFAM; SSF54719; Fe,Mn superoxide dismutase (SOD), C-terminal domain; 1.
DR SUPFAM; SSF46609; Fe,Mn superoxide dismutase (SOD), N-terminal domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002037}.
FT DOMAIN 120..180
FT /note="Manganese/iron superoxide dismutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02777"
FT DOMAIN 207..250
FT /note="Manganese/iron superoxide dismutase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02777"
SQ SEQUENCE 254 AA; 29780 MW; EC9693196AAD064A CRC64;
MFSRGIIRPL SRRSIHTVPK LPTHKVWQEK GIPGLLSAEG YQTAWTDYQN YLLTNLTLLT
NGTSSELKSP YETLLHTAKQ TTSQHIFHYS SMAHNNHFFF EQLSDKEIAS KTKPSRFLME
KLMHEDVLDM DQFRNKILKM AEESYGQGWI FLIETQDKNL KFINCHNDGT PYYYAKSQLL
DLNGGLNEND FNYLQDLKEK AANGEKDFNL PLLAINYWDY MYIKDYGVSG KAEYLSNLWE
HINWDVINKR LFQI
//
