ID   C5P5R7_COCP7            Unreviewed;       547 AA.
AC   C5P5R7;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   SubName: Full=HMG box domain containing protein {ECO:0000313|EMBL:EER28057.1};
GN   ORFNames=CPC735_033930 {ECO:0000313|EMBL:EER28057.1};
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929 {ECO:0000313|EMBL:EER28057.1, ECO:0000313|Proteomes:UP000009084};
RN   [1] {ECO:0000313|EMBL:EER28057.1, ECO:0000313|Proteomes:UP000009084}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735 {ECO:0000313|Proteomes:UP000009084};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EER28057.1}.
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DR   EMBL; ACFW01000025; EER28057.1; -; Genomic_DNA.
DR   RefSeq; XP_003070202.1; XM_003070156.1.
DR   AlphaFoldDB; C5P5R7; -.
DR   GeneID; 9695697; -.
DR   KEGG; cpw:CPC735_033930; -.
DR   VEuPathDB; FungiDB:CPC735_033930; -.
DR   HOGENOM; CLU_022445_4_0_1; -.
DR   OrthoDB; 1539933at2759; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd01389; HMG-box_ROX1-like; 1.
DR   Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   PANTHER; PTHR45803; SOX100B; 1.
DR   PANTHER; PTHR45803:SF5; SOX100B; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; HMG-box; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00267};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00267}.
FT   DOMAIN          204..272
FT                   /note="HMG box"
FT                   /evidence="ECO:0000259|PROSITE:PS50118"
FT   DNA_BIND        204..272
FT                   /note="HMG box"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          108..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..352
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        116..130
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..347
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   547 AA;  61477 MW;  3679556D4BBE061A CRC64;
     MNHQHPPSPP PSADGEIKNP FHDLSQNNTL QSPFLRNHHP FTTMYARQDY PFAKIDVDNR
     DVTEVMAGYP QTGAFNSVPG AEFPQITSVP QLTYVRAMQL TGNQHHQHHA VDMGRTGSGG
     SSSSRGSTGM HKFQEADKSR VQRMTRVRKR TRTARSDKRN LIITAPLSVL TKDMVHIPIR
     DMKAWVNRSA EVRRKEVAAK NGKIARPMNS FMLYRSAYAE RTKEWCAQNN HQVVSRASGQ
     SWPLEPKEIR DLYEGYATIE RDNHQKAHPD YKFAPNKTQN TPKKKQTATK DDENSDLDDA
     GFDIPACSRP VGTWPSRSDA DEGFGSRTST PFDKDSSYES RTSTPFDHPN GDMYMHHSDI
     NRSSWEMVNP GRPLPGVLSP PEQSHYYQPS IHQSVLGPGI EDVTYKKMGV PGVSYEPQGT
     LNGLPGNPHP DLLPTQPSRT VEDSTQVDPQ LLEFSHHQQQ SVTEAGSYPG HLNLWQVPPT
     TQHYVPTSIP AQQAEEYLSA HAQQTGFHHG APLMESRDVW GEGHNGEAVK QEFGQEFDQW
     LTGHHTY
//