ID   C5PBN0_COCP7            Unreviewed;       541 AA.
AC   C5PBN0;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 66.
DE   SubName: Full=WD domain, G-beta repeat containing protein {ECO:0000313|EMBL:EER25357.1};
GN   ORFNames=CPC735_064570 {ECO:0000313|EMBL:EER25357.1};
OS   Coccidioides posadasii (strain C735) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=222929 {ECO:0000313|EMBL:EER25357.1, ECO:0000313|Proteomes:UP000009084};
RN   [1] {ECO:0000313|EMBL:EER25357.1, ECO:0000313|Proteomes:UP000009084}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C735 {ECO:0000313|Proteomes:UP000009084};
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EER25357.1}.
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DR   EMBL; ACFW01000041; EER25357.1; -; Genomic_DNA.
DR   RefSeq; XP_003067502.1; XM_003067456.1.
DR   AlphaFoldDB; C5PBN0; -.
DR   GeneID; 9692984; -.
DR   KEGG; cpw:CPC735_064570; -.
DR   VEuPathDB; FungiDB:CPC735_064570; -.
DR   HOGENOM; CLU_022996_1_1_1; -.
DR   OrthoDB; 125824at2759; -.
DR   Proteomes; UP000009084; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR012952; BING4_C_dom.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   InterPro; IPR040315; WDR46/Utp7.
DR   PANTHER; PTHR14085:SF3; WD REPEAT-CONTAINING PROTEIN 46; 1.
DR   PANTHER; PTHR14085; WD-REPEAT PROTEIN BING4; 1.
DR   Pfam; PF08149; BING4CT; 1.
DR   Pfam; PF00400; WD40; 1.
DR   SMART; SM01033; BING4CT; 1.
DR   SMART; SM00320; WD40; 4.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 1.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   REPEAT          281..322
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          368..447
FT                   /note="BING4 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01033"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          467..487
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          50..77
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        467..483
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   541 AA;  61331 MW;  A443FC0D370CB660 CRC64;
     MEVETSRPSV PSQRRSAHLT AEARESALRL ADAQKQYGRG KKVNIKSIKD KKLRSQLRTL
     ENKYKDASLK AKDAEVLLEH ESGFLEPEGE LERTYKVRQD EIRDNVGIET AKKGFELKLE
     ELGPYRADYT RNGKMLLLAG RKGHVATMDW REGKLGCELQ IGETVRDAKW LHNELFFAVA
     QKRYVYIYDH KGVELHCLDK HVEATHLEFL PYHFLLASAA TSGYLKYTDT STGQLVAELP
     TRQGSPTSLC QNPYNAILHV GHQNGTVTLW SPNSTTPLVK ALAHRGPVRS IAVDRQGRYM
     VSTGQDMRMA IWDIRMFKEV HNYSVHQPGA TVSISDRGLT AVGWGTKVSV WKGLFDAAAA
     SERKVQSPYM AWGGDGQRIE NVRWCPYEDI LGVAHDKGFS SLIVPGAGEP NFDASEANPY
     ENVKQRQEAE VKSLLTKLQP EMISLNPDFV GSLDLVSDKI KREERDLDKK NEDPIERLKN
     RGRGRNSALR RYLRKRGSKN VIDEKRVKAE TLRREQKSRV QGKIRQEREE LGPALARFVK
     K
//