ID C5XCK0_SORBI Unreviewed; 665 AA.
AC C5XCK0;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Galectin domain-containing protein {ECO:0000259|PROSITE:PS51304};
GN ORFNames=SORBI_3002G068800 {ECO:0000313|EMBL:EER98156.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EER98156.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EER98156.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004323}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 31 family.
CC {ECO:0000256|ARBA:ARBA00008661}.
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DR EMBL; CM000761; EER98156.1; -; Genomic_DNA.
DR RefSeq; XP_002461635.1; XM_002461590.1.
DR AlphaFoldDB; C5XCK0; -.
DR STRING; 4558.C5XCK0; -.
DR EnsemblPlants; EER98156; EER98156; SORBI_3002G068800.
DR GeneID; 8075086; -.
DR Gramene; EER98156; EER98156; SORBI_3002G068800.
DR KEGG; sbi:8075086; -.
DR eggNOG; KOG2287; Eukaryota.
DR HOGENOM; CLU_017063_2_0_1; -.
DR InParanoid; C5XCK0; -.
DR OMA; NGYFTAH; -.
DR OrthoDB; 357901at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000000768; Chromosome 2.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0008378; F:galactosyltransferase activity; IBA:GO_Central.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR CDD; cd00070; GLECT; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.90.550.50; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001079; Galectin_CRD.
DR InterPro; IPR002659; Glyco_trans_31.
DR PANTHER; PTHR11214; BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR11214:SF245; OS07G0194800 PROTEIN; 1.
DR Pfam; PF00337; Gal-bind_lectin; 1.
DR Pfam; PF01762; Galactosyl_T; 1.
DR SMART; SM00908; Gal-bind_lectin; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51304; GALECTIN; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 177..387
FT /note="Galectin"
FT /evidence="ECO:0000259|PROSITE:PS51304"
FT REGION 137..164
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 665 AA; 74162 MW; 97BD1A6ABA227BE4 CRC64;
MPPAPAARKK RLVRAGLLTA AVGYFAFVLL FELPLLPFLA SSSSPAATSS SSSLPFQHPR
RRELEAAAAA FTSPYSPARP SKPAFPAAAP GPSSTPRLPI FSSLLLLPRP NATATPFDTT
AADAFAAAKP HLAHLQSIPN PASASTSASA PASSPPPPTC PASISVHREQ LPYDGVRVVE
LPCGLAVGSH VTVVARPRPA RPEYDPKIAE RKDGEAAVMV SQFMVELVGT KAVDGEAPPR
ILHFNPRIRG DYSRKPVIEM NSCYRMQWGQ SQRCEGFASR PAEDTVDGQL KCEKWIHDDD
NKSEESKMKW WVKRLIGRPK DVHISWPYPF TEGKLFVMTL TAGLEGYHVN VDGRHVASFP
YRTGYSLEDA TALSLNGDID IESIFASSLP NSHPSFAPER YLEMSEQWKA PPLPTEPVEL
FIGILSAASH FAERMAVRKS WMMYTRKSSN IVARFFVALN GKKEVNAELK KEAEFFQDIV
IVPFIDSYDL VVLKTVAIAE YGVRVVPAKY VMKCDDDTFV RIDSVLDQVK KGRNDKSVYV
GSINYFHRPL RSGKWAVTYE EWPEEVYPNY ANGPGYVISS DIAHYIVSEF DNQTLRLFKM
EDVSMGMWVE KFNKTRRPVE IRHDVRFYQS GCYNGYFTAH YQSPQHMICL WRKLQSGSAR
CCNVR
//
