ID C5XDR5_SORBI Unreviewed; 712 AA.
AC C5XDR5;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE RecName: Full=GTP diphosphokinase {ECO:0000256|ARBA:ARBA00013251};
DE EC=2.7.6.5 {ECO:0000256|ARBA:ARBA00013251};
GN ORFNames=SORBI_3002G217400 {ECO:0000313|EMBL:EER96802.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EER96802.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EER96802.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- SIMILARITY: Belongs to the RelA/SpoT family.
CC {ECO:0000256|ARBA:ARBA00007476}.
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DR EMBL; CM000761; EER96802.1; -; Genomic_DNA.
DR RefSeq; XP_002460281.1; XM_002460236.1.
DR AlphaFoldDB; C5XDR5; -.
DR STRING; 4558.C5XDR5; -.
DR EnsemblPlants; EER96802; EER96802; SORBI_3002G217400.
DR GeneID; 8081003; -.
DR Gramene; EER96802; EER96802; SORBI_3002G217400.
DR KEGG; sbi:8081003; -.
DR eggNOG; KOG1157; Eukaryota.
DR HOGENOM; CLU_012300_7_1_1; -.
DR InParanoid; C5XDR5; -.
DR OMA; AMNKERT; -.
DR OrthoDB; 1396at2759; -.
DR Proteomes; UP000000768; Chromosome 2.
DR GO; GO:0009507; C:chloroplast; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0008728; F:GTP diphosphokinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0015969; P:guanosine tetraphosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd05399; NT_Rel-Spo_like; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR007685; RelA_SpoT.
DR PANTHER; PTHR21262:SF0; GTP DIPHOSPHOKINASE RSH3, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR21262; GUANOSINE-3',5'-BIS DIPHOSPHATE 3'-PYROPHOSPHOHYDROLASE; 1.
DR Pfam; PF13328; HD_4; 1.
DR Pfam; PF04607; RelA_SpoT; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00954; RelA_SpoT; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR PROSITE; PS51831; HD; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT DOMAIN 236..340
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 1..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 98..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 712 AA; 78931 MW; BA2254467C66CFB5 CRC64;
MSLPAISLYT SPPGAVYSSE FDPTSRGSSP STTAAPPPPA ASHRLPSGGG GGGLSCLFSS
PAAAAAPPRA PAHDDLGALW HDRSDDLSVV GGGYSYSHSH SSSPLKRRDL HHNHHSPVSV
FQGPSSSSPS RSPPASWLAA RDRDRLFAGF VRNALGSCVD YAPPSSPRPE VGAGELAFEL
DENLAEAGPA CEPYARELLA SAQDRHRIFH EELVVKAFLE AEKAHRGQTR ASGEPYLQHC
VETAVLLAKI GANATVVSAG LLHDTIDDSF IDYDHIFHMF GAGVADLVEG VSKLSHLSKL
ARDNNTASRT VEADRLHTML LAMADARAVL IKLADRLHNM KTLEALSLVK QQRFAKETKE
IFVPLANRLG IASWKDQLEN LCFKYLNPEE YKELSSKLTE SFDEELITSA VGKLDKGLRD
AGVSYHNLSG RHKSLYSIHS KMLKKNLTME EIHDIHGLRL VVDTVEDCYE ALCVVHKLWP
RVTGRFKDYI SRPKLNGYRS LHTVVMSEGV HPFEVQIRTK EMHLQAEYGF AAHWRYKEGT
CRHSFVLQMV EWARWVLTWQ CEAMNKERTA SLGNDDTVRP PCPFPLHSEE CPYSYTRQCN
HDGPLFVILL EHDKMSVQEF PANSTVMDLM DRVGANSSRW SPYSIPVKED LRPRVNHEPI
CDPNRKLSMG DVVELTPALP RKSLSGYREE IQRMYDRGGF ALSTRGGGSR RC
//
