ID C5Z0Q2_SORBI Unreviewed; 538 AA.
AC C5Z0Q2;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 24-JAN-2024, entry version 69.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=SORBI_3009G056500 {ECO:0000313|EMBL:EES19093.1};
OS Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX NCBI_TaxID=4558 {ECO:0000313|EMBL:EES19093.1, ECO:0000313|Proteomes:UP000000768};
RN [1] {ECO:0000313|EMBL:EES19093.1, ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=19189423; DOI=10.1038/nature07723;
RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT "The Sorghum bicolor genome and the diversification of grasses.";
RL Nature 457:551-556(2009).
RN [2] {ECO:0000313|Proteomes:UP000000768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX PubMed=29161754; DOI=10.1111/tpj.13781;
RA McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT a transcriptome atlas, and signatures of genome organization.";
RL Plant J. 93:338-354(2018).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
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DR EMBL; CM000768; EES19093.1; -; Genomic_DNA.
DR RefSeq; XP_002440663.1; XM_002440618.1.
DR AlphaFoldDB; C5Z0Q2; -.
DR STRING; 4558.C5Z0Q2; -.
DR EnsemblPlants; EES19093; EES19093; SORBI_3009G056500.
DR GeneID; 8071210; -.
DR Gramene; EES19093; EES19093; SORBI_3009G056500.
DR KEGG; sbi:8071210; -.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_039112_1_0_1; -.
DR InParanoid; C5Z0Q2; -.
DR OMA; FYHFSMN; -.
DR OrthoDB; 988298at2759; -.
DR Proteomes; UP000000768; Chromosome 9.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR CDD; cd16469; RING-H2_RNF24-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045191; MBR1/2-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22937; E3 UBIQUITIN-PROTEIN LIGASE RNF165; 1.
DR PANTHER; PTHR22937:SF206; OS05G0163400 PROTEIN; 1.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000768};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 486..527
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 538 AA; 58245 MW; 7DB126B7598B633A CRC64;
MAGHHHNNTH ASRMDHVNRF QSEPQPFGPK LFMHSRTDAA NGALSSGYGG APIRPNDIPS
SSHTGQSHIQ HSDAPGTMLA SYSGYPHAGS SSSIYAPHNT HHPPPLSYPH RSEDNFIPSS
HMDDRRVALK RRNPIIHPVD GVNIGSSYAG SSSNPQFSRY MPPNHIPAPE PCPSRITSNM
GSRYWSDHPF GGHGGSQRNV RGRHDHNPIH LGHNPGVPCA SSSTHGPPHQ TNVIGHPRST
AVPQDRAHFS IPPRVAAPGT DGNSSMVFRE RPYYSAPQRT NINAPPVPTP PGSSDSLHFV
HGGYAPRAAP PNTISTYPAP AFATSNNTVT VTHEPDIPSY RPAVPSYPPA TSAAASSIHA
EAATSPRHLG HVALGSGGSA RSRRLRDSYH AFRPLIIEEN NLRGPAAERF MMLDELVIHE
SREDSDPHWD MRLDIDDMSY EELLALGERI GNVNTGLADE KLSSCVMEIT CCSSARTHGD
TESARCVICL EDYKFKDSIG KLKCGHDYHA DCIKKWLQVK NACPVCKASA ADDSGGTE
//
