ID   C5ZYJ2_9HELI            Unreviewed;       602 AA.
AC   C5ZYJ2;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 43.
DE   SubName: Full=General glycosylation pathway protein {ECO:0000313|EMBL:EES90210.1};
GN   Name=pglF {ECO:0000313|EMBL:EES90210.1};
GN   ORFNames=HCAN_1505 {ECO:0000313|EMBL:EES90210.1};
OS   Helicobacter canadensis MIT 98-5491.
OC   Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=537970 {ECO:0000313|EMBL:EES90210.1, ECO:0000313|Proteomes:UP000007032};
RN   [1] {ECO:0000313|EMBL:EES90210.1, ECO:0000313|Proteomes:UP000007032}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13241 {ECO:0000313|Proteomes:UP000007032};
RX   PubMed=19542273; DOI=10.1128/JB.00729-09;
RA   Loman N.J., Snyder L.A., Linton J.D., Langdon R., Lawson A.J.,
RA   Weinstock G.M., Wren B.W., Pallen M.J.;
RT   "Genome sequence of the emerging pathogen Helicobacter canadensis.";
RL   J. Bacteriol. 191:5566-5567(2009).
CC   -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC       {ECO:0000256|ARBA:ARBA00007430}.
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DR   EMBL; CM000776; EES90210.1; -; Genomic_DNA.
DR   RefSeq; WP_006656990.1; NZ_DS990369.1.
DR   AlphaFoldDB; C5ZYJ2; -.
DR   STRING; 537970.HCAN_1505; -.
DR   eggNOG; COG1086; Bacteria.
DR   HOGENOM; CLU_013560_5_2_7; -.
DR   OrthoDB; 9769113at2; -.
DR   Proteomes; UP000007032; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003869; Polysac_CapD-like.
DR   PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR   PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR   Pfam; PF02719; Polysacc_synt_2; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007032};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        86..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          278..561
FT                   /note="Polysaccharide biosynthesis protein CapD-like"
FT                   /evidence="ECO:0000259|Pfam:PF02719"
SQ   SEQUENCE   602 AA;  67471 MW;  2766393042E0581C CRC64;
     MIKSAIFRPS NLKRILFFLV IDIVVSYFAL VLSYDLRFSF QVPLEFNSGV ILAFLVLIVL
     KIGALWVFKI YLVPWRFFGL SEALKIIYAH ILAYGIFTLL FFLGFFDKFP LSVVIIDFVI
     SGILIGGIRI SKRIYLENSP KNSPKPALIF GANTQAATLI KSSLNSEIPF YPLAIIDEDK
     KEQGNYISNL KVYPKTALKE LLEKHKIKSV ILTKPYAKPP LEKLFNELTQ MGIEEIKIAS
     MLKEDKPLED ISIEDLLSRP SKDLDKEVIG EFIANKTILI TGAGGSIGSE IVRQCVEFGA
     KRLILLDHSE YNLYAITEEL TRKISSKNDK KSLLRTAMFS ILEKDRLLEL MQEEKPDIVV
     HAAAYKHVPL CEYNQKSAIE NNILGSKNVI DSAIEIKVPK IVIISTDKAV RPTNVMGATK
     RVVELYAQNV DSKQSEIVAV RFGNVLGSSG SVVPKFKAQI QSGGPITVTH PEITRYFMLI
     PEACRLVLQA SAIAKGGEIF ILDMGEPVKI VDLAKNMLKL YGKEEEIEIV FSGLRPGEKL
     YEELLIGESE GKTKYPSIQV ARPTSYDINK LNQDISELLE TQEVVAKLKE IVVEFNHNAH
     GQ
//