ID C6AV66_RHILS Unreviewed; 772 AA.
AC C6AV66;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family {ECO:0000313|EMBL:ACS57663.1};
DE EC=1.1.5.8 {ECO:0000313|EMBL:ACS57663.1};
DE Flags: Precursor;
GN OrderedLocusNames=Rleg_3417 {ECO:0000313|EMBL:ACS57663.1};
OS Rhizobium leguminosarum bv. trifolii (strain WSM1325).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=395491 {ECO:0000313|EMBL:ACS57663.1, ECO:0000313|Proteomes:UP000002256};
RN [1] {ECO:0000313|EMBL:ACS57663.1, ECO:0000313|Proteomes:UP000002256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM1325 {ECO:0000313|EMBL:ACS57663.1,
RC ECO:0000313|Proteomes:UP000002256};
RX PubMed=21304718;
RA Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R.,
RA Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinikova G.,
RA Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V., Denton M.,
RA Yates R., Howieson J.;
RT "Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain
RT WSM1325, an effective microsymbiont of annual Mediterranean clovers.";
RL Stand. Genomic Sci. 2:347-356(2010).
CC -!- COFACTOR:
CC Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC Evidence={ECO:0000256|ARBA:ARBA00001931};
CC -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00008156}.
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DR EMBL; CP001622; ACS57663.1; -; Genomic_DNA.
DR RefSeq; WP_012758777.1; NC_012850.1.
DR AlphaFoldDB; C6AV66; -.
DR KEGG; rlg:Rleg_3417; -.
DR HOGENOM; CLU_018478_1_0_5; -.
DR OrthoDB; 9794322at2; -.
DR Proteomes; UP000002256; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0047519; F:quinate dehydrogenase (quinone) activity; IEA:UniProtKB-EC.
DR GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR CDD; cd10280; PQQ_mGDH; 1.
DR Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 1.
DR InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR InterPro; IPR017511; PQQ_mDH.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR NCBIfam; TIGR03074; PQQ_membr_DH; 1.
DR PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR PANTHER; PTHR32303:SF4; QUINOPROTEIN GLUCOSE DEHYDROGENASE; 1.
DR Pfam; PF01011; PQQ; 3.
DR SMART; SM00564; PQQ; 5.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ACS57663.1}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 492..513
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 772 AA; 83984 MW; 11BAFC8651BDA80B CRC64;
MKFLATLFCI VLALIGLALI GGGAWLLRLG GSPYYAIIGL AYLVAALLLW RRKTAGGLIV
LLVAVFTLPW ALWESGLNFW ALFARLMSPI ALAGFALLFA PSLSPAANRK LFYGGALVTA
LIFVAGFGLS FVPHGIIRPS ADITAYKTAK GDNSPSDWPS YGRSTAGDRY SPFDQINRGN
VSKLDLAWTY RTGKGDGADQ NTPLQIGDTV YTCTPTDVIA ALDADTGKPR WAFDPKATAP
YWQRCRGLGY YKMPTEAQSA DGLCNERLVQ TTIDARLLEI DSRTGTPCKD FGVNGTVQLS
QGMGEVKTGY YFQTSAPLIA RNLIVVGGWV TDNQEVGEPS GVIRAFNVVT GELEWAWDLG
NPEITKLPPK GQTYTRATPN MWTTAAFDDK LGLIYAPLGN TTPDYYGVNR PAFADQYNAT
LVALDVTTGR EKWKFQTVHH DIWDYDLPAQ PILIDLPDGN GATMPALLQT TKRGQLFLLD
RRTGTPLAEV QEKPVPQQGG VPEEKLSPTQ PYSVGMPTIG AERVTEQTAW GLTMFDQLAC
RIAFRKMRYD GDFTPIGTQY AIQQPGNLGG LNWGSVSVDL PNNRVFMNDI RVPSLFALIP
REEYVDFALT TTAHGPSAPQ RGTPYAMATE MWTSRLRVPC TQPPFGTVTA VDLKTRKIAW
QVPAGTAEEL GPFKIKTKLP MPMGLPSYAG TSATAGGVVF FAGFQDYYIR AYDAENGAEL
WRYPLPVGSS ATPMTYVSPK TGKQYVLISV GGAPYSKDVG DYVLAFSLKD GA
//
