ID C6BAZ7_RHILS Unreviewed; 621 AA.
AC C6BAZ7;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Carbamoyl-phosphate synthase L chain ATP-binding {ECO:0000313|EMBL:ACS61255.1};
GN OrderedLocusNames=Rleg_6512 {ECO:0000313|EMBL:ACS61255.1};
OS Rhizobium leguminosarum bv. trifolii (strain WSM1325).
OG Plasmid pR132505 {ECO:0000313|EMBL:ACS61255.1,
OG ECO:0000313|Proteomes:UP000002256}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX NCBI_TaxID=395491 {ECO:0000313|EMBL:ACS61255.1, ECO:0000313|Proteomes:UP000002256};
RN [1] {ECO:0000313|EMBL:ACS61255.1, ECO:0000313|Proteomes:UP000002256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WSM1325 {ECO:0000313|Proteomes:UP000002256};
RC PLASMID=Plasmid pR132505 {ECO:0000313|Proteomes:UP000002256};
RX PubMed=21304718;
RA Reeve W., O'Hara G., Chain P., Ardley J., Brau L., Nandesena K., Tiwari R.,
RA Copeland A., Nolan M., Han C., Brettin T., Land M., Ovchinikova G.,
RA Ivanova N., Mavromatis K., Markowitz V., Kyrpides N., Melino V., Denton M.,
RA Yates R., Howieson J.;
RT "Complete genome sequence of Rhizobium leguminosarum bv. trifolii strain
RT WSM1325, an effective microsymbiont of annual Mediterranean clovers.";
RL Stand. Genomic Sci. 2:347-356(2010).
CC -!- COFACTOR:
CC Name=biotin; Xref=ChEBI:CHEBI:57586;
CC Evidence={ECO:0000256|ARBA:ARBA00001953};
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DR EMBL; CP001627; ACS61255.1; -; Genomic_DNA.
DR RefSeq; WP_012760748.1; NC_012854.1.
DR AlphaFoldDB; C6BAZ7; -.
DR KEGG; rlg:Rleg_6512; -.
DR HOGENOM; CLU_000395_3_1_5; -.
DR OrthoDB; 9763189at2; -.
DR Proteomes; UP000002256; Plasmid pR132505.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06850; biotinyl_domain; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR011761; ATP-grasp.
DR InterPro; IPR005481; BC-like_N.
DR InterPro; IPR001882; Biotin_BS.
DR InterPro; IPR011764; Biotin_carboxylation_dom.
DR InterPro; IPR005482; Biotin_COase_C.
DR InterPro; IPR000089; Biotin_lipoyl.
DR InterPro; IPR005479; CbamoylP_synth_lsu-like_ATP-bd.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR011054; Rudment_hybrid_motif.
DR InterPro; IPR011053; Single_hybrid_motif.
DR PANTHER; PTHR18866; CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE; 1.
DR PANTHER; PTHR18866:SF33; METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF02785; Biotin_carb_C; 1.
DR Pfam; PF00289; Biotin_carb_N; 1.
DR Pfam; PF00364; Biotin_lipoyl; 1.
DR Pfam; PF02786; CPSase_L_D2; 1.
DR SMART; SM00878; Biotin_carb_C; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
DR SUPFAM; SSF51246; Rudiment single hybrid motif; 1.
DR SUPFAM; SSF51230; Single hybrid motif; 1.
DR PROSITE; PS50975; ATP_GRASP; 1.
DR PROSITE; PS50979; BC; 1.
DR PROSITE; PS00188; BIOTIN; 1.
DR PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR PROSITE; PS00867; CPSASE_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Biotin {ECO:0000256|ARBA:ARBA00023267};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00409}; Plasmid {ECO:0000313|EMBL:ACS61255.1}.
FT DOMAIN 1..449
FT /note="Biotin carboxylation"
FT /evidence="ECO:0000259|PROSITE:PS50979"
FT DOMAIN 120..322
FT /note="ATP-grasp"
FT /evidence="ECO:0000259|PROSITE:PS50975"
FT DOMAIN 537..617
FT /note="Lipoyl-binding"
FT /evidence="ECO:0000259|PROSITE:PS50968"
SQ SEQUENCE 621 AA; 66852 MW; 641D0889C1097270 CRC64;
MMESLLIANR GEIARRIIRT AKMLGIRTIA VYSEADAGLP FVSEADEAIA IGPSPARESY
LSQERILDAA RKTGAAAIHP GYGFLSENAG FAEAVEKAGI IWVGAPPAAI RAMGLKDAAK
ELMQAAGVPV TPGYIGADQS EERLTAEADI IGYPVLIKAV AGGGGKGMRR VDRPQDFAEL
LASCRREAAA AFGDDRVLIE RYIANPRHIE VQVFADKLGN CVHLFERDCS LQRRHQKVIE
EAPAPGLDAA TRAVICDAAV KAARAVNYVG AGTIEFIADA SEGLREDRIW FMEMNTRLQV
EHPVTEAITG EDLVLWQLKV ASGEPLPKMQ DEIAMNGWAF EARLYAENPA AGYLPSIGRL
EHLRLPETVR VDSGVEQGDD ITAFYDPMIA KVIAHGPNRE AALSKLAAAC AGIEVWPVRS
NAGLLARIAI DPDFRAARID TGFLDRHDER LVATEPSETA IDSAATALLK NTDGNPWTAL
TGFRIAGAED KRVRIRIGDH LHWGQSRPEF EANTITIGET TVLFEAGNAW PISLPVASEV
EASQSAGDGA ILSPMPGLVI SVDVADGDRV AKGDRLLTVE AMKMEHSLRA PFDGIVEKLQ
VSSGIRVSEN QLVVSIVKEQ D
//
