ID C6E390_GEOSM Unreviewed; 726 AA.
AC C6E390;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Helicase, RecD/TraA family {ECO:0000313|EMBL:ACT19082.1};
DE EC=3.1.11.5 {ECO:0000313|EMBL:ACT19082.1};
GN OrderedLocusNames=GM21_3054 {ECO:0000313|EMBL:ACT19082.1};
OS Geobacter sp. (strain M21).
OC Bacteria; Thermodesulfobacteriota; Desulfuromonadia; Geobacterales;
OC Geobacteraceae; Geobacter.
OX NCBI_TaxID=443144 {ECO:0000313|EMBL:ACT19082.1};
RN [1] {ECO:0000313|EMBL:ACT19082.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M21 {ECO:0000313|EMBL:ACT19082.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C.,
RA Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.,
RA Lovley D.;
RT "Complete sequence of Geobacter sp. M21.";
RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001661; ACT19082.1; -; Genomic_DNA.
DR AlphaFoldDB; C6E390; -.
DR STRING; 443144.GM21_3054; -.
DR KEGG; gem:GM21_3054; -.
DR eggNOG; COG0507; Bacteria.
DR HOGENOM; CLU_007524_0_3_7; -.
DR OrthoDB; 9763659at2; -.
DR GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd17933; DEXSc_RecD-like; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 1.10.10.2220; -; 1.
DR Gene3D; 2.30.30.940; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01488; RecD_like; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR006345; DNA_helicase_RecD-like.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029493; RecD-like_HHH.
DR InterPro; IPR041451; RecD-like_SH13.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; TIGR01448; recD_rel; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF14490; HHH_4; 1.
DR Pfam; PF14520; HHH_5; 1.
DR Pfam; PF18335; SH3_13; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00278; HhH1; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ACT19082.1};
KW Hydrolase {ECO:0000313|EMBL:ACT19082.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 127..146
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 191..210
FT /note="Helix-hairpin-helix DNA-binding motif class 1"
FT /evidence="ECO:0000259|SMART:SM00278"
FT DOMAIN 343..552
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 726 AA; 78812 MW; A6A7A1D4821AE167 CRC64;
MKETPPTENV DRLSGSLERV TFHSEETGFC VLRVKVAGQR DLVTVTGAAA SVTPGEYLEC
TGSWHNDRTH GMQFKAGHIK VVPPTTLEGI EKYLGSGMVH GIGAHFAKVL VKSFDAAVFD
VIENHPERLL ELPGIGRKRM ESVAGAWVEQ KAIREIMVFL QSNGLGTARA VRIYKSYGNE
AIFKVTENPY RLALEIHGIG FKTADLLAAK LGIAPDSMIR AQAGVRHVLQ EMSTSGHCAA
LRAELAESTA SLLEIPQPVI ESAIEAELAA ENLVADQISG SPCVFLAPLY KAEVGVASGI
CRLRAGTPPW GGIVAEEAIP WVESQKGITL SASQRDAIRL ALKSKVVVVT GGPGVGKTTL
VNSILGVIGR RPLRVTLCAP TGRAAKRLAE STGMEAKTIH RLLEFDPQSF GFKRCKENPL
HTDLLVMDEA SMVDVVLMNK LLPAIPDHAG LIIVGDVDQL PSVGPGSVLS DIIESGAVPT
VRLTEIFRQA AGSRIIVNAH RINRGELPLK DEGKELADFY FIPAATPEDI HDKLLQVVRE
RIPKRFGFDP VREVQVLTPM NRGGLGTRSL NAELQGVLNG RGEPKVERFG TSYAPGDKVI
QTVNNYEKEV FNGDIGRIVE IRPEEGALTV DFDDRLVEYA FAELDEVSLA YATSIHKSQG
SEYTAVVIPL AMQHYTMLER NLLYTAVTRG KKLVVVIGEQ KALAMAVQNQ KSHRRLTRLA
GRIALT
//
