ID C6H3P1_AJECH Unreviewed; 464 AA.
AC C6H3P1;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU369086};
GN ORFNames=HCDG_00052 {ECO:0000313|EMBL:EER44473.1};
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712 {ECO:0000313|EMBL:EER44473.1, ECO:0000313|Proteomes:UP000002624};
RN [1] {ECO:0000313|Proteomes:UP000002624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase which catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. {ECO:0000256|RuleBase:RU369086}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369086}.
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DR EMBL; GG692419; EER44473.1; -; Genomic_DNA.
DR AlphaFoldDB; C6H3P1; -.
DR STRING; 544712.C6H3P1; -.
DR VEuPathDB; FungiDB:HCDG_00052; -.
DR eggNOG; KOG4134; Eukaryota.
DR HOGENOM; CLU_036411_1_0_1; -.
DR OMA; DEYGVLY; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR GO; GO:0055029; C:nuclear DNA-directed RNA polymerase complex; IEA:UniProt.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:UniProtKB-UniRule.
DR Gene3D; 2.40.50.1060; -; 1.
DR Gene3D; 3.30.1490.120; RNA polymerase Rpb7-like, N-terminal domain; 1.
DR InterPro; IPR036898; RNA_pol_Rpb7-like_N_sf.
DR InterPro; IPR041178; RPA43_OB.
DR InterPro; IPR045113; Rpb7-like.
DR PANTHER; PTHR12709:SF5; DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43; 1.
DR PANTHER; PTHR12709; DNA-DIRECTED RNA POLYMERASE II, III; 1.
DR Pfam; PF17875; RPA43_OB; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU369086};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU369086};
KW Reference proteome {ECO:0000313|Proteomes:UP000002624};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU369086}.
FT DOMAIN 239..407
FT /note="RPA43 OB"
FT /evidence="ECO:0000259|Pfam:PF17875"
FT REGION 1..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 188..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 283..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..111
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 195..209
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..322
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 464 AA; 50763 MW; 3A0BB466428FF93F CRC64;
MSLDAMDIDS VPVSPERKRK NREKDGHSAK KRKHEVSNYA AQPETEESSP KPKKKEKKDR
KHKKHKHHDD FEPSAPTLPA SPNPRSQITK KHKHQSPATQ DEEEEEPPTT SRKPLTKASA
SRLESTYTDS MESSPFHLIT ATLYVPLSPI SISPTHALSS LQAEHLSPLL LTYFPPVRGI
VLAYSNASIS STPPSPSSPS TPHNPDESPK PQPLTLAMSA GEYGVLYVYL TATFLVFRPE
RGQPLEGWIN VQSDGFLGAV VYNLFSVGIE RRRLPADWRW VAPGQESTTS TSEAVSPKDR
GGSVGVGVDD DDDDDDDDKS SDFDSDKENF RPLPASSAAM LDHSTQYQSN GGLEPPFEAF
EDASAGYFQT RSGRRVRGMV RFRVRDVDVI PGAEHDKGFI SIEGTMLSPE EEAKLVEEER
KRAGFAPSSS SSAVAAAAAA GVSGGSGDVR WPGDIKCFYC YCCC
//
