ID   C6H3W3_AJECH            Unreviewed;       248 AA.
AC   C6H3W3;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Aminoglycoside phosphotransferase domain-containing protein {ECO:0000259|Pfam:PF01636};
GN   ORFNames=HCDG_01284 {ECO:0000313|EMBL:EER45705.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER45705.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aminoglycoside phosphotransferase family.
CC       {ECO:0000256|ARBA:ARBA00006219}.
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DR   EMBL; GG692419; EER45705.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6H3W3; -.
DR   STRING; 544712.C6H3W3; -.
DR   VEuPathDB; FungiDB:HCDG_01284; -.
DR   HOGENOM; CLU_1337183_0_0_1; -.
DR   OMA; HEGCRES; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd05120; APH_ChoK_like; 1.
DR   Gene3D; 3.90.1200.10; -; 1.
DR   InterPro; IPR002575; Aminoglycoside_PTrfase.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   PANTHER; PTHR21310:SF57; AMINOGLYCOSIDE PHOSPHOTRANSFERASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR21310; AMINOGLYCOSIDE PHOSPHOTRANSFERASE-RELATED-RELATED; 1.
DR   Pfam; PF01636; APH; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT   DOMAIN          120..146
FT                   /note="Aminoglycoside phosphotransferase"
FT                   /evidence="ECO:0000259|Pfam:PF01636"
SQ   SEQUENCE   248 AA;  28102 MW;  A367092FFC692E55 CRC64;
     MDPFTPKSML LAPHPAMARG SGNDMFDRYQ VIHLNEHRVR KQAHEGCRES DSMLYIAANT
     NIPVPKVNDT KLDAEDGFSY IVMEYVLGRS LEDAWMKLSP DQRGTQGPHL LPNDNHIIHF
     AHGDLSPQNI LVDEGGRITA IIDWDILRMR MDFPRERKML DHPRYFQSIF PPKYKQNFSA
     LAYLAHFEPL VPGSLPLNPF PTVGRMEIGY HVQMKLSEVG LGFGESPCGT NPGTGIHAEH
     SLYDPHFI
//