ID   C6HB53_AJECH            Unreviewed;       410 AA.
AC   C6HB53;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   24-JAN-2024, entry version 44.
DE   SubName: Full=Aldose 1-epimerase {ECO:0000313|EMBL:EER42476.1};
GN   ORFNames=HCDG_03935 {ECO:0000313|EMBL:EER42476.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER42476.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the aldose epimerase family.
CC       {ECO:0000256|ARBA:ARBA00006206}.
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DR   EMBL; GG692422; EER42476.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HB53; -.
DR   STRING; 544712.C6HB53; -.
DR   VEuPathDB; FungiDB:HCDG_03935; -.
DR   HOGENOM; CLU_031753_0_0_1; -.
DR   OMA; TNHTYFG; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd09019; galactose_mutarotase_like; 1.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR047215; Galactose_mutarotase-like.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   PANTHER; PTHR10091:SF6; 1-EPIMERASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G13240)-RELATED; 1.
DR   PANTHER; PTHR10091; ALDOSE-1-EPIMERASE; 1.
DR   Pfam; PF01263; Aldose_epim; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..410
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002965985"
SQ   SEQUENCE   410 AA;  45042 MW;  00EEF3675AF92133 CRC64;
     MYIKLPALLS SVLLLGAPPL ASSKPTTSSD PFQPYVISAK NIQATLIPYG ATLTSLLVND
     RDGKQQDVVV GYDDPKQYKI DTETNHTYFG CIVGRYANRI KNGSFELDGV KYDITKNENH
     DTQTLHGGVI GYDQRPWTVV NHTENSITFS LLDTGFEGFP GEVITYATLS VRSSCTKDDT
     KCETKLTAKT VSLALTEETP IMLSHHIYWN LNGFKKPNVL EDTTLQLPLS KRFIKIDSAA
     IPTGELADTA TAFGGALDFT QPKLIGKDIA SAKNCGANCT GYDNAFIIDR PNSESDWTSS
     PETMAVVLRM ASRTTGISMQ VTTNQKAVQI YSCNNQNGTI PVKESQTNRN KMEGGYEYVD
     VINKYGCIVI ETEGWIDGIS NPEWGQNPYQ IYSPETGPAV NWATFTFGNI
//