ID C6HFC5_AJECH Unreviewed; 403 AA.
AC C6HFC5;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 08-NOV-2023, entry version 46.
DE SubName: Full=Sulfite oxidase {ECO:0000313|EMBL:EER41002.1};
GN ORFNames=HCDG_04648 {ECO:0000313|EMBL:EER41002.1};
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712 {ECO:0000313|EMBL:EER41002.1, ECO:0000313|Proteomes:UP000002624};
RN [1] {ECO:0000313|Proteomes:UP000002624}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mo-molybdopterin; Xref=ChEBI:CHEBI:71302;
CC Evidence={ECO:0000256|ARBA:ARBA00001924};
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DR EMBL; GG692424; EER41002.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HFC5; -.
DR STRING; 544712.C6HFC5; -.
DR VEuPathDB; FungiDB:HCDG_04648; -.
DR eggNOG; KOG0535; Eukaryota.
DR HOGENOM; CLU_003827_5_2_1; -.
DR OMA; VAQWARH; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.650; -; 1.
DR Gene3D; 3.90.420.10; Oxidoreductase, molybdopterin-binding domain; 1.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR005066; MoCF_OxRdtse_dimer.
DR InterPro; IPR008335; Mopterin_OxRdtase_euk.
DR InterPro; IPR000572; OxRdtase_Mopterin-bd_dom.
DR InterPro; IPR036374; OxRdtase_Mopterin-bd_sf.
DR PANTHER; PTHR19372:SF7; SULFITE OXIDASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR19372; SULFITE REDUCTASE; 1.
DR Pfam; PF03404; Mo-co_dimer; 1.
DR Pfam; PF00174; Oxidored_molyb; 1.
DR PRINTS; PR00407; EUMOPTERIN.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF56524; Oxidoreductase molybdopterin-binding domain; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Molybdenum {ECO:0000256|ARBA:ARBA00022505};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT DOMAIN 38..246
FT /note="Oxidoreductase molybdopterin-binding"
FT /evidence="ECO:0000259|Pfam:PF00174"
FT DOMAIN 273..394
FT /note="Moybdenum cofactor oxidoreductase dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03404"
SQ SEQUENCE 403 AA; 44482 MW; F4E3781DCEA90AC5 CRC64;
MISKLDPEPV RPLNREAPLH ELVSSFITQA PDAYNRNHSA IPEIDAATHV VSVGGDVPNP
LQLSIEQLRH DFPQHEVLAA LQCAGNRRHT MRTKLKEVVG LDWMDGAVMN CTWRGPRLRD
ILIKAGVKGC NNYNDDHETN AMASGAVNGT SNGHTAAGEI GPQMHVAFTC DQLRCQDDSN
YGVSIELWRA MAVDREVILA LEMNNKPLQP AYGYPVRVVV PGVAGARWVK WLDTISVVPH
ESPNFYQQHD YKILPPEALT WEIAEEYWPK VPAMQCMPVN SVVAVPNDDS TVSLPLSGEL
EIKGFAVPFG ADGPVTRVEV SVDGGKTWVD TELDYGPHDS NKSKNKWAWV LWRAAVKVEK
GRNKTIYSRA TDAGGNTQQE MSPWNLRGVG YNGYGASWNV SVV
//
