ID   C6HI74_AJECH            Unreviewed;       475 AA.
AC   C6HI74;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   22-FEB-2023, entry version 37.
DE   SubName: Full=Universal stress protein family domain-containing protein {ECO:0000313|EMBL:EER40002.1};
GN   ORFNames=HCDG_06224 {ECO:0000313|EMBL:EER40002.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER40002.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG692428; EER40002.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HI74; -.
DR   STRING; 544712.C6HI74; -.
DR   VEuPathDB; FungiDB:HCDG_06224; -.
DR   eggNOG; ENOG502RYEB; Eukaryota.
DR   HOGENOM; CLU_018542_0_2_1; -.
DR   OMA; GMRDIES; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   CDD; cd00293; USP_Like; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR006015; Universal_stress_UspA.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR47815; UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10; 1.
DR   PANTHER; PTHR47815:SF1; UNIVERSAL STRESS PROTEIN A FAMILY PROTEIN C25B2.10; 1.
DR   Pfam; PF00582; Usp; 1.
DR   PRINTS; PR01438; UNVRSLSTRESS.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT   DOMAIN          143..281
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
FT   REGION          1..47
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          68..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          282..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          342..475
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        285..300
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        349..368
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        383..407
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        413..428
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        429..443
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   475 AA;  52557 MW;  34BBD8CB7C891195 CRC64;
     MSKSASTNTW PDTSSSALGS DGTASSHRDD ASVFTLGGST AMPTDVPPRR QSIQFNMEAA
     AAELSKKRIG ATRGTLTSRI GRMPSPPPPR HDEYHPDTTL TSHDVSAYNR GVSFDTFDNR
     DATDFSLTLN YKHRDYHPTR RSRTFLCGTD QNDYSDFALE WLIDELVDDG DEIVCLRVVE
     KDSKIANDAS MEERRYRQEA QKLLDQVIAK NSHDEKTISL VLEFAVGKVQ EIIQRMIQIY
     EPSALIVGTR GRSLGGMQGL LPGSVSKYCL QQSPIPVIVV RSSTKREKKK QKRLGNPTRH
     RYNHILRLND MKSGRVFDKA RNSDSIATKQ PEEEAAVAQA IGEQDMGGSL AIRNTSRDPR
     LSFSRDTAST RSTDDKDDTS EGTRSLSIPN SESAAPNFSS ALKNQRIESP AITDDEGDED
     EGDSPGDDND YDSEARDRSR QHGSQDAAPS PKKPPLVPIT NATTTEYTSD VDERH
//