ID   C6HM50_AJECH            Unreviewed;       577 AA.
AC   C6HM50;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=OTU domain-containing protein {ECO:0000259|PROSITE:PS50802};
GN   ORFNames=HCDG_07166 {ECO:0000313|EMBL:EER38297.1};
OS   Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS   (Histoplasma capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544712 {ECO:0000313|EMBL:EER38297.1, ECO:0000313|Proteomes:UP000002624};
RN   [1] {ECO:0000313|Proteomes:UP000002624}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H143 {ECO:0000313|Proteomes:UP000002624};
RA   Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA   Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA   Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA   Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA   Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA   Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA   Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA   Nusbaum C., Birren B.W.;
RT   "The genome sequence of Ajellomyces capsulatus strain H143.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; GG692431; EER38297.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6HM50; -.
DR   STRING; 544712.C6HM50; -.
DR   VEuPathDB; FungiDB:HCDG_07166; -.
DR   HOGENOM; CLU_460752_0_0_1; -.
DR   OMA; GNCLYYS; -.
DR   Proteomes; UP000002624; Unassembled WGS sequence.
DR   GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR   CDD; cd22756; OTU_OTUD3-like; 1.
DR   Gene3D; 3.90.70.80; -; 1.
DR   InterPro; IPR003323; OTU_dom.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR12419:SF7; OTU DOMAIN-CONTAINING PROTEIN 3; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS50802; OTU; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002624}.
FT   DOMAIN          51..200
FT                   /note="OTU"
FT                   /evidence="ECO:0000259|PROSITE:PS50802"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          302..384
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          411..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        302..358
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        359..378
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        411..440
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..476
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..513
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        534..577
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   577 AA;  63453 MW;  FF4D1464C5B59B76 CRC64;
     MARRKSHSSG PAGNRTSPPE DSAMKMHLEM AMAGMPSKSS LKLGCLDYFN LYAMPILGDD
     QLYGSVDRHI EIRERLVQHM RDNADYFRDF TADVGGERRA PRRSAAQASR LAYTNVDRAA
     TAEGQAAKFK LMLNEMKGQN AWGGSPEIQA FCQAYGLDVL VYSEDGVQRF QNFFAEADPN
     RGVIHLAFHS FQHYSSVRNL DGPHVGLPKL PERIKAADLI YRKIISKEPM IDQKINPENI
     PPEPQNPTVT HPADMHWMIT IFGQRVPAND DESIRAMIGE CSPNITAALN RLVENKNRAL
     PRSSIPFSTS LSSTTTSNSV PTPRSGGSRP KSSSTMNTSS GAVQGSSSRS SSRHSVTSKR
     SANDSDLDEE DGTVRTATRR SRGRCRKRRM LEDVTVDILG NRSEVVAIEV NHNNDDEEGD
     GHNKYNGSNR DNDHHDGTNR NGDLNAGQGN LDVGIGTGSR TGTSTATRTL TGTRTLSPEP
     IAKEHYTKQK QKQKQTDGVI RSIENDDDDY GGDPCSVRTL SPSASQGSEA TNSKEEDDID
     DEYADADADE DEDEDEDEDG DGDDDADSDY KDEEDDE
//