ID C6JNL6_FUSVA Unreviewed; 407 AA.
AC C6JNL6;
DT 01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 01-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Peptidase, M16 family {ECO:0000313|EMBL:EES62614.1};
DE EC=3.4.24.- {ECO:0000313|EMBL:EES62614.1};
GN ORFNames=FVAG_00303 {ECO:0000313|EMBL:EES62614.1};
OS Fusobacterium varium ATCC 27725.
OC Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC Fusobacterium.
OX NCBI_TaxID=469618 {ECO:0000313|EMBL:EES62614.1, ECO:0000313|Proteomes:UP000004505};
RN [1] {ECO:0000313|EMBL:EES62614.1, ECO:0000313|Proteomes:UP000004505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27725 {ECO:0000313|EMBL:EES62614.1,
RC ECO:0000313|Proteomes:UP000004505};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Strauss J., Ambrose C.E.,
RA Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Fusobacterium varium ATCC 27725.";
RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the peptidase M16 family.
CC {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EES62614.1}.
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DR EMBL; ACIE02000002; EES62614.1; -; Genomic_DNA.
DR RefSeq; WP_005947199.1; NZ_GL987995.1.
DR AlphaFoldDB; C6JNL6; -.
DR STRING; 469618.FVAG_00303; -.
DR GeneID; 77468072; -.
DR eggNOG; COG0612; Bacteria.
DR HOGENOM; CLU_009902_3_2_0; -.
DR Proteomes; UP000004505; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 2.
DR InterPro; IPR011249; Metalloenz_LuxS/M16.
DR InterPro; IPR011765; Pept_M16_N.
DR InterPro; IPR001431; Pept_M16_Zn_BS.
DR InterPro; IPR007863; Peptidase_M16_C.
DR PANTHER; PTHR11851:SF149; GH01077P; 1.
DR PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR Pfam; PF00675; Peptidase_M16; 1.
DR Pfam; PF05193; Peptidase_M16_C; 1.
DR SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 2.
DR PROSITE; PS00143; INSULINASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EES62614.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004505}.
FT DOMAIN 14..143
FT /note="Peptidase M16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00675"
FT DOMAIN 165..339
FT /note="Peptidase M16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05193"
SQ SEQUENCE 407 AA; 46358 MW; 4328984809881318 CRC64;
MNIEIRKLDN GIPVLMENID SVSTVSLGIF VKTGSRNEYP DESGVSHFIE HMMFKGTKNR
SAKEISELID NEGGLINAYT SRDTTAYYIQ MLSSKIDTGI DVLSDMFLNS TFTQENLDKE
RNVIIEEIRM YDDIPEEIVH DENVKYAITG VQSNIVLGTI ESLNNITREK FLKYFDEQYI
ASNLVVSVAG KIDFDHVVAE LNKGLGKFRD SNFKRDMDTS FTINHGENRI KKETNQVHLC
FNTRGNSQIE DMKYPGAIIS SVLAGNMSSR LFQKIREERG LAYSVYSYGT AFIEGGLFTI
YAGTTKESYQ EVIDIIKAEF EDIKKNGITP YELQKSKNQF LSMLTFSLEN SKGKMTRMAS
TYMLYGRVTE IDEIISKIEN ITLEDIKKTA EYLFQEEFYS CTILGDI
//
