ID C6LPU2_GIAIB Unreviewed; 2658 AA.
AC C6LPU2;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Coiled-coil protein {ECO:0000313|EMBL:EET01976.1};
GN ORFNames=GL50581_761 {ECO:0000313|EMBL:EET01976.1};
OS Giardia intestinalis (strain ATCC 50581 / GS clone H7) (Giardia lamblia).
OC Eukaryota; Metamonada; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX NCBI_TaxID=598745 {ECO:0000313|EMBL:EET01976.1, ECO:0000313|Proteomes:UP000002488};
RN [1] {ECO:0000313|EMBL:EET01976.1, ECO:0000313|Proteomes:UP000002488}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 50581 / GS clone H7 {ECO:0000313|Proteomes:UP000002488};
RX PubMed=19696920; DOI=10.1371/journal.ppat.1000560;
RA Franzen O., Jerlstrom-Hultqvist J., Castro E., Sherwood E., Ankarklev J.,
RA Reiner D.S., Palm D., Andersson J.O., Andersson B., Svard S.G.;
RT "Draft genome sequencing of giardia intestinalis assemblage B isolate GS:
RT is human giardiasis caused by two different species?";
RL PLoS Pathog. 5:E1000560-E1000560(2009).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET01976.1}.
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DR EMBL; ACGJ01000948; EET01976.1; -; Genomic_DNA.
DR EnsemblProtists; EET01976; EET01976; GL50581_761.
DR VEuPathDB; GiardiaDB:GL50581_761; -.
DR OMA; EQFRIQN; -.
DR OrthoDB; 5317726at2759; -.
DR Proteomes; UP000002488; Unassembled WGS sequence.
DR Gene3D; 1.10.287.1490; -; 2.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR23159:SF54; CENTROSOMAL PROTEIN 135KDA, ISOFORM B-RELATED; 1.
DR PANTHER; PTHR23159; CENTROSOMAL PROTEIN 2; 1.
DR Pfam; PF12796; Ank_2; 2.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF57997; Tropomyosin; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT REGION 1040..1069
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 458..541
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 567..601
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1421..1567
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1617..1735
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1764..2064
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2107..2253
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2289..2316
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2366..2473
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 2658 AA; 298125 MW; BB0A4861665FC42B CRC64;
MTETWFSAAK RADYGAVRSL GSKYFRAHND DDGGNTALLY AISSNNMQLI SYLAPHEVRE
VNAFGWSALM FAAYYGNCDA VKIFLDDEKG MRTQEEYKGI PTGATALLIA ATRGHANCVT
LLYPVERSAS GWNDLFLAAF THNAALVARH DSLVSTRDVL GRTAMMYLVM FPRHSTLASL
EKCIVHLAQA QQGAIDACTK TALMYAVENN NIDAVQLLLQ LTTLEIRKQM EAKDEYTALM
IAASRGYNDI VAQLLPKEAG IVTSNGVTAL MLAVRYNQIE AARLLKDVES EFQTSGPFDV
FSPAATALSI ARYYQRQELL SLLGAGSLQI TTTEEKSLYP GPEGLAKSPK SMTMSSALTS
QRKDHIHLSI NEDSRVAATI SPIFKSNLNA SRPTPTHHST GELQDNDQLV LTDTQTVAIL
SNTEALERLK ETNQDLATRV FTMQRSMQLE SIEQQNTIDK LDIELNLTRQ RQSELESKLK
LAEEKITMYK DYSQQAYKHN ESLSKKFAEL KDSYDSVTQE NAQLSTSLAS LRSEKASLEA
VHKDLALLFD ELQRQIKVDK STTDSQITKY STEILALQKD LSEMKQALTT AQDEASTNEQ
NARLATEELA QLKPRYQDLT EKMSDLKVLY EETDVHNRAV QQENSLLKEE LDKATTSLAL
LQEESINIKE RLTELEASNA TLHTTVTDLN KEKISQALVC EKLSGQNAGM EDQVQELQHS
LQRATSETES LSARLAEHVL ESQNLRATIS QLQKDLTSLT DEKDVLQTQL CADQERLTIT
KSDLSAARQE VAMLKETLDK VSSDYRRLEE DSQRTQMQLI EQQELTQRAE STKATLETRL
VTIEEQLLES QRGVNVGQQD LAALRTELQI MTKKYECLEI HAAELETTTA ELTREKATLI
AKTKDTTEEK ESLVGQLNSL SFQAEQLQND KSALERQVSD LLVIISQEQE TQASLKKQVG
DASRKSAELD EEIIRLRDKL NKTMEEMSVL TSKLATSEES IAKAEAKFAS LSKERNSLFK
ELSTVTKELT DLKLTNESLE KDAQSTQQKL KEVNLSKKSL EQSSSNSSKK IANLSSAKAA
LEKQLSNATA HISDLESQLT TLEKKDSESK QALLAKDKSI DEANRSVSQL KRQLKDTKAD
NETVQKNIIA LTKELTSLQL LKEQSDATIL KLTKAVADEK EENQSLNEQL NEANKQISTL
RNAQDAIELA RISATDRVEE LLSENKGLGE LIADLKGIIT NTQNALQEVT EERNSAVDRI
KQADNKIAAY VSDQQTSKAS MDQLRADLST MEGANKRLQK DIATRVELYE ELERKNDQLS
KQNSELIGYQ ATLEEQLHSK DAALNDGQLA RENLERELML ANKNCHDLRE EYAELQQMLA
SKRVDIENMS ESKLSADAAL QKAIDKCSAF QAEVTLGQKS IESMAQHIKV LEGEISKLKE
KNAALLGSLS ETEASKESVE RDLKVAKGKI TETEERISEI EQEKARIFKG LQVITGEKDG
IERRLKEKSQ LVEEQHAELE ALKKALAASN ELNTDLTSNS ESSIKSLQQL SRQLAESQGE
VAGLKRGAEL TACRLAELEA LCDEQARTIS TKNSTTTELQ MERDLLFKKL AACTASSKEL
EDTLSTMQKE YSDQSKKLME LEADNLVLQR NISSSAKATE DLTSALTAAN QTVAETGKKI
LELEERREIL ERSLAHINKR NTTLETEKEQ LAKNLIEANR AAAAAEAEQN SLAKETISLR
DLVTELEGKL SVSATTISAK SAMILDLENQ VDTMTREHSD LMALKLELET ERDSLQARTK
AYTETIAELE KSKRDVDQLL ATANNKLLEQ EMAFQTAERT LKSLKEKLKS TKQEKDTALS
VQADLKNELT TLSETAKMLE DTVNSLTKQI SERDRDNESL RTVANGHRTN EEKAQEEIER
QRNIILDYQQ QVSQAGLERL ALTQQIDQEK KKAMDIMASK QELQDDLQAF RKRYSELDTE
YDSLKKALAS NNTTMEKLTL QCSSLTAELS TLKLQYNSTR LELESAQMLV ETTKRGSVSL
QGEIDKLSRD LQQANEVNAQ LRVEQGILQQ SLDNTNASLN TLVTQGETLS KATADSNKKL
HDYMSELTLK NNEVDSLKRS LARKEADIEE LCVRMNSKIE EVRQLHSDKE QAEARICVLL
SENSDLKMTI NGLTSTLDSQ KQSVKDLEGE LASAHGELKN TSSEVWRLEL ELKTINENNK
DSHNRLETLN QQIASYEKQV SSITEEKEGL SKLISQLKLT INELTLAKQE VSAGLAAEKV
VSLKLSSEND DLSKRLESGK AAYEELSTEH KSLLEKYHTL NSMKELANTE LDALRSMTNM
SKADLDKFSA DYEQFRAHTL QDRATIAKLQ SDLEKLESKN KFLADEKAQC TKIIKSLNKD
IVDLKLQLHS LDQSKESAAR RLSVLGSDKE ALITEVNDLR KQICDQERLI QELQKQSKEA
ERLKEDLAHM NATMGEFADM YAVTINKYAD AMRHHNDIAK FMPKYNTYMS DSGLMTDARL
RHFLENNKAL LDEKALTERK FKRLSEYVNY IKAELVNTDM KYLAWIQHKT AVFNKSVANT
QPTSRPDFMT QTIDEQARRL STALEPTDFS ASDEINIERA SLDRASLAKQ LQAREIKYDA
TRTAQYDHYP SRPSSQNN
//
