ID C6PZT4_9CLOT Unreviewed; 265 AA.
AC C6PZT4;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Methionine synthase {ECO:0000313|EMBL:EET85241.1};
DE EC=2.1.1.13 {ECO:0000313|EMBL:EET85241.1};
GN ORFNames=CcarbDRAFT_4301 {ECO:0000313|EMBL:EET85241.1};
OS Clostridium carboxidivorans P7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=536227 {ECO:0000313|EMBL:EET85241.1, ECO:0000313|Proteomes:UP000004198};
RN [1] {ECO:0000313|EMBL:EET85241.1, ECO:0000313|Proteomes:UP000004198}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P7 {ECO:0000313|EMBL:EET85241.1,
RC ECO:0000313|Proteomes:UP000004198};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA Goodwin L., Pitluck S., Larimer F., Land M.L., Hauser L., Hemme C.L.;
RT "The draft genome of Clostridium carboxidivorans P7.";
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the vitamin-B12 dependent methionine synthase
CC family. {ECO:0000256|ARBA:ARBA00010398}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EET85241.1}.
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DR EMBL; ACVI01000100; EET85241.1; -; Genomic_DNA.
DR RefSeq; WP_007063186.1; NZ_GG770693.1.
DR AlphaFoldDB; C6PZT4; -.
DR STRING; 536227.Ccar_13140; -.
DR KEGG; cck:Ccar_13140; -.
DR PATRIC; fig|536227.13.peg.2752; -.
DR eggNOG; COG1410; Bacteria.
DR OrthoDB; 358252at2; -.
DR Proteomes; UP000004198; Unassembled WGS sequence.
DR GO; GO:0008705; F:methionine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0042558; P:pteridine-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR InterPro; IPR000489; Pterin-binding_dom.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF00809; Pterin_bind; 1.
DR SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR PROSITE; PS50972; PTERIN_BINDING; 1.
PE 3: Inferred from homology;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EET85241.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004198};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EET85241.1}.
FT DOMAIN 1..265
FT /note="Pterin-binding"
FT /evidence="ECO:0000259|PROSITE:PS50972"
SQ SEQUENCE 265 AA; 29402 MW; 373B304D60F26246 CRC64;
MLIIGELINT SRKLIREAVE KKDGEYIKQV AKAQEEAGAT YIDVNCGTCI ETEVETMEWL
VDNILQVTSL PLCIDSPNPL ALQAGLKKAA NGKLMINSIT FETPRWNAVL PLVKEFNTKI
IALCIDDGGM PKTNEDRIRI ADSIITKLTG EGINIDDIYI DPLIKPVSAG QKNGIEVLQA
IQNIMEGHPG VHTTCGLSNI SYSLPARKVL NTLFMVQTMA RGMDSYIMDP TNKEMRRALI
ASQTLLGQDR FSRKFIKAFR EGLYD
//
