ID C6WBU7_ACTMD Unreviewed; 309 AA.
AC C6WBU7;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Transcriptional regulator, LysR family {ECO:0000313|EMBL:ACU37514.1};
GN OrderedLocusNames=Amir_3625 {ECO:0000313|EMBL:ACU37514.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU37514.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU37514.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; CP001630; ACU37514.1; -; Genomic_DNA.
DR RefSeq; WP_015802402.1; NC_013093.1.
DR AlphaFoldDB; C6WBU7; -.
DR STRING; 446462.Amir_3625; -.
DR KEGG; ami:Amir_3625; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_4_11; -.
DR OrthoDB; 3828349at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 1..58
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 309 AA; 33066 MW; 94DEC752BB7B666D CRC64;
MDVENVRAFV AAAESGRLGD AAVELGISQQ AVSKRVGALE RAVGVALFAR TPRGVRLTLD
GAVFLPHARA VLRAVERAAR SVRPENRVLR VDVPNLRTAP STALRAFHAA HPEVALEVVT
LPENHLGGAL EAVRAGAVDA SFRAVPLARA DLPDGVRTAR AVDSGLELLV GPRHPLADRA
ELAPVKLAGH RVWVPGIRPG TEWARFYRDF AGAFGAAVDG AGPHFGDEAL LEVLAGSAEH
ATIVGSGDHY LWPAVYDLRR IPLRDPTPVY PHRLLWSTVN DHPGLADLRA FLTAGRARAP
EPVWEPSWA
//
