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Database: UniProt
Entry: C6WEL4_ACTMD
LinkDB: C6WEL4_ACTMD
Original site: C6WEL4_ACTMD 
ID   C6WEL4_ACTMD            Unreviewed;       250 AA.
AC   C6WEL4;
DT   22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   22-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=Transcriptional regulator, LuxR family {ECO:0000313|EMBL:ACU37814.1};
GN   OrderedLocusNames=Amir_3947 {ECO:0000313|EMBL:ACU37814.1};
OS   Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS   / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Actinosynnema.
OX   NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU37814.1, ECO:0000313|Proteomes:UP000002213};
RN   [1] {ECO:0000313|EMBL:ACU37814.1, ECO:0000313|Proteomes:UP000002213}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC   NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX   PubMed=21304636; DOI=10.4056/sigs.21137;
RA   Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA   Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA   Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA   Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA   Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA   Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT   "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL   Stand. Genomic Sci. 1:46-53(2009).
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DR   EMBL; CP001630; ACU37814.1; -; Genomic_DNA.
DR   AlphaFoldDB; C6WEL4; -.
DR   STRING; 446462.Amir_3947; -.
DR   KEGG; ami:Amir_3947; -.
DR   eggNOG; COG2197; Bacteria.
DR   HOGENOM; CLU_1109590_0_0_11; -.
DR   Proteomes; UP000002213; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR039420; WalR-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR43214:SF24; TRANSCRIPTIONAL REGULATORY PROTEIN NARL-RELATED; 1.
DR   PANTHER; PTHR43214; TWO-COMPONENT RESPONSE REGULATOR; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT   DOMAIN          182..247
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
SQ   SEQUENCE   250 AA;  27056 MW;  B3B4E167071EF805 CRC64;
     MTSTLQARPR ADRFERLLSD RSGVRLLGVP EVSGASRTRL LDEFAALASA RGALVARGRA
     RGGAYGLFQD AFGSVSAHGR ERDVVLLLRG LLRAPRALGM TEDELRRAVD AVLGSLPGLV
     LLLDDVHLAD RPSLALLEHL VRRGAGSPLL VVLAHEPRSC PPPLAALLVA AERESLATVL
     RLPVDGHRLT QRERTVLVVL AEGLTADAIA RRLDISPRTV HRHLQHLYRK LGTTDRLATV
     LRAQELGLLG
//
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