ID C6WI94_ACTMD Unreviewed; 461 AA.
AC C6WI94;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Magnesium protoporphyrin chelatase, putative {ECO:0000313|EMBL:ACU36137.1};
GN OrderedLocusNames=Amir_2192 {ECO:0000313|EMBL:ACU36137.1};
OS Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064
OS / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Actinosynnema.
OX NCBI_TaxID=446462 {ECO:0000313|EMBL:ACU36137.1, ECO:0000313|Proteomes:UP000002213};
RN [1] {ECO:0000313|EMBL:ACU36137.1, ECO:0000313|Proteomes:UP000002213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 /
RC NRRL B-12336 / IMRU 3971 / 101 {ECO:0000313|Proteomes:UP000002213};
RX PubMed=21304636; DOI=10.4056/sigs.21137;
RA Land M., Lapidus A., Mayilraj S., Chen F., Copeland A., Del Rio T.G.,
RA Nolan M., Lucas S., Tice H., Cheng J.F., Chertkov O., Bruce D., Goodwin L.,
RA Pitluck S., Rohde M., Goker M., Pati A., Ivanova N., Mavromatis K.,
RA Chen A., Palaniappan K., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Han C., Chain P., Tindall B.J., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Actinosynnema mirum type strain (101).";
RL Stand. Genomic Sci. 1:46-53(2009).
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DR EMBL; CP001630; ACU36137.1; -; Genomic_DNA.
DR RefSeq; WP_015801026.1; NC_013093.1.
DR AlphaFoldDB; C6WI94; -.
DR STRING; 446462.Amir_2192; -.
DR KEGG; ami:Amir_2192; -.
DR eggNOG; COG1239; Bacteria.
DR HOGENOM; CLU_043779_0_0_11; -.
DR OrthoDB; 9760760at2; -.
DR Proteomes; UP000002213; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR PANTHER; PTHR30267; PROTEIN KINASE PRKA; 1.
DR PANTHER; PTHR30267:SF2; PROTEIN PRKA; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002213}.
FT DOMAIN 168..226
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|Pfam:PF00158"
SQ SEQUENCE 461 AA; 49998 MW; 4A9CBCA354B23AC7 CRC64;
MTSRLPTTVG ELRASGHQPR GVKAEIRENL LAALRSGRDP WPGIVGFDRT VLPQLERALL
AGHDVVLLGE RGQGKTRLLR TIVGLLDEWT PVIEGAELGE HPLDPITPES KRRAAELGDD
LPVVWRHRDD RFAEKLATPD TSVGDLVGDV DPVKVAQGRS LGDPETIHYG LLPRSHRGVI
AVNELPDLAE RIQVSLLNVM EERDIQIRGY TLRLPLDVLL VATANPEDYT NRGRIITPLK
DRFGAEIRTH YPLEVAAEVD LVRQEADLVA EVGDHLLEVV ARFVRHLRES SAIDQRSGVS
ARFAVAAAET VAAAALRRSA LTGESPAVAR PVDLESVPEV LRGKLEFEAG EEGREQEVLT
HLLRRSVADT ARAALAGVDL RQLAEAVSDG HPVATGERVT AAELLGALPE LPVLHEVATR
LGADPSGPAG RIASAVELAL ESLYLTRRLA KDADDDRSVY G
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