ID C6X529_FLAB3 Unreviewed; 489 AA.
AC C6X529;
DT 22-SEP-2009, integrated into UniProtKB/TrEMBL.
DT 22-SEP-2009, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Permease, possible major facilitator superfamily {ECO:0000313|EMBL:ACU07517.1};
GN OrderedLocusNames=FIC_01067 {ECO:0000313|EMBL:ACU07517.1};
OS Flavobacteriaceae bacterium (strain 3519-10).
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=531844 {ECO:0000313|EMBL:ACU07517.1, ECO:0000313|Proteomes:UP000001512};
RN [1] {ECO:0000313|EMBL:ACU07517.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3519-10 {ECO:0000313|EMBL:ACU07517.1};
RX PubMed=18622572; DOI=10.1007/s00792-008-0178-2;
RA Raymond J.A., Christner B.C., Schuster S.C.;
RT "A bacterial ice-binding protein from the Vostok ice core.";
RL Extremophiles 12:713-717(2008).
RN [2] {ECO:0000313|EMBL:ACU07517.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=3519-10 {ECO:0000313|EMBL:ACU07517.1};
RA Christner B.C., Raymond J.A., Schuster S.C.;
RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP001673; ACU07517.1; -; Genomic_DNA.
DR AlphaFoldDB; C6X529; -.
DR STRING; 531844.FIC_01067; -.
DR KEGG; fba:FIC_01067; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_000960_28_3_10; -.
DR Proteomes; UP000001512; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17321; MFS_MMR_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR42718:SF24; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR42718; MAJOR FACILITATOR SUPERFAMILY MULTIDRUG TRANSPORTER MFSC; 1.
DR Pfam; PF07690; MFS_1; 2.
DR PRINTS; PR01036; TCRTETB.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001512};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 212..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 341..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 368..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..483
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 489 AA; 51899 MW; 5FB19192A95D6AD6 CRC64;
MKDFNSNMEN RLQGNDTILA GFILAVLTFW LFANSMLNIA PLMSRQLGIG ANSMNIAVSL
AALFSGIFVV VFGGLADQIG RTRILRIGLY LSIVGSIIVA LIPAGDAAEP LLLVGRALQG
LSAACIMPTS LGLLKILWEG PAQQRAISFW SMGTFGGSGL AALFAGIIAT NLGWRWIFIL
SAVVAVIALY LLKELPESKK ESAGKYRPDW IGILLFLAAI VCLELFITSG GTLGYLSFTS
LALLVAGIVV AVLFYYYEIR TTNHFFDFSL FKNSVFSGAI ICNFLMNATS GIIIVALTLM
QSAAGYSAQQ AGLLTLGYAI SVILFIRSGE RMMRKIGARK PMVWGSLVVA LATLLLMQTY
LMTETYRILA IIAFTLFGTG LAFFATPATT AALSNLPADQ SGAGAGVFKM ASSLGAGFGI
AIVAGIFTSV SGSGDTQDWL PELFLGKQDN INYRLAAIPA LSAALIFALL SAIVANTKIP
KDGGKIKKN
//
