ID C7JHI3_ACEP3 Unreviewed; 486 AA.
AC C7JHI3;
DT 13-OCT-2009, integrated into UniProtKB/TrEMBL.
DT 13-OCT-2009, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Transporter of xanthine/uracil {ECO:0000313|EMBL:BAH99437.1};
GN OrderedLocusNames=APA01_12910 {ECO:0000313|EMBL:BAH99437.1};
OS Acetobacter pasteurianus (strain NBRC 105184 / IFO 3283-01).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acetobacter.
OX NCBI_TaxID=634452 {ECO:0000313|EMBL:BAH99437.1, ECO:0000313|Proteomes:UP000000948};
RN [1] {ECO:0000313|EMBL:BAH99437.1, ECO:0000313|Proteomes:UP000000948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 105184 / IFO 3283-01 {ECO:0000313|Proteomes:UP000000948};
RX PubMed=19638423; DOI=10.1093/nar/gkp612;
RA Azuma Y., Hosoyama A., Matsutani M., Furuya N., Horikawa H., Harada T.,
RA Hirakawa H., Kuhara S., Matsushita K., Fujita N., Shirai M.;
RT "Whole-genome analyses reveal genetic instability of Acetobacter
RT pasteurianus.";
RL Nucleic Acids Res. 37:5768-5783(2009).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; AP011121; BAH99437.1; -; Genomic_DNA.
DR RefSeq; WP_012812939.1; NC_013209.1.
DR AlphaFoldDB; C7JHI3; -.
DR STRING; 634452.APA01_12910; -.
DR KEGG; apt:APA01_12910; -.
DR PATRIC; fig|634452.3.peg.1360; -.
DR eggNOG; COG2233; Bacteria.
DR HOGENOM; CLU_017959_8_2_5; -.
DR BioCyc; APAS634452:APA01_RS06520-MONOMER; -.
DR Proteomes; UP000000948; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR017588; UacT-like.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR NCBIfam; NF037981; NCS2_1; 1.
DR NCBIfam; TIGR03173; pbuX; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 116..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..439
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 486 AA; 51036 MW; 62689C1E13FD4C30 CRC64;
MKAARNVPQA VHPVDEFLPF WQLGVYGLQH VLTFYAASVI VPILLASALG LSHDALEHLI
EADLFTCGIA SLIQAVGIGP LGVKLPLLQG VTFVSVTPMI AIGTAAGGGI DGLHQIFGAV
IVAGIFSYFV APFFSRLIRF FPPVVTGSVI LVIGLALLPV AANDIVNGQG TGAMQNPVSL
RNVAYGLGTL LCILAVQRFF KGFIGTIAVL VGLIMGTLVA WILGDAHFGD VSSAPLLTIV
RPLYFGMPSF HIVPILSLII VMMISMLETT GDVFATGAIV EKKITPRDIT RAIRADGAAT
MLGGIFNSFP YTCFAENVGL VRLTGVKSRW VVAAAALIMM VMGCLPKLAV LMACVPLPVL
GGAALAMFAA VAVVGIQTLA QVDFDNQNNG IIVGTSVGLG MLATAQPHIA DHFPAWAQII
FGSGITLGAM SAIILHLIFN HGTHDAVVED IEATPQPATT HPEMWKNVVV ISEDKLGSRP
PQSLSR
//
